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Specificity of deoxycytidylate antibodies

Reddy, M Vijayaraj and Jacob, TM (1981) Specificity of deoxycytidylate antibodies. In: Immunology Letters, 3 (4). pp. 231-235.

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Antibodies to deoxycytidylate (dpC) were elicited in rabbits using a thyroglobulin (Tg) conjugate of dpC. The specificity of the antibodies was determined by measuring the inhibition of the binding of [3H]dpC to the antibodies by various non-radioactive nucleotides or derivatives. The antibodies were found to distinguish dpC from pC and DNA from RNA, probably due to their specificity for the conformation of the deoxycytidylate.

Item Type: Journal Article
Publication: Immunology Letters
Publisher: Elsevier Science
Additional Information: Copy right of this article belongs to Elsevier Science.
Keywords: Thyroglobulin protein carrier;anti-deoxycytidylate antibody; radioimmunoassay;antibody specificity;DNA;RNA
Department/Centre: Division of Biological Sciences > Biochemistry
Date Deposited: 09 Jan 2010 05:47
Last Modified: 09 Jan 2010 05:47
URI: http://eprints.iisc.ac.in/id/eprint/22767

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