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Deoxyribonucleic acid methylation in mycobacteria

Srivastava, R and Gopinathan, KP and Ramakrishnan, TV (1981) Deoxyribonucleic acid methylation in mycobacteria. In: Journal of Bacteriology, 148 (2). pp. 716-719.

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Deoxyribonucleic acid modification in six strains of mycobacteria was investigated. The presence of 5-methylcytosine in the virulent strain Mycobacterium tuberculosis H37Rv and its absence in the avirulent strain M. tuberculosis H37Ra and other saprophytic, fast-growing mycobacteria appear to be the salient features. However, deoxyribonucleic acid from M. smegmatis SN2 lysogenized with the temperature phage I3 showed the presence of 5-methylcytosine. All of the strains had N6-methyladenine.

Item Type: Journal Article
Publication: Journal of Bacteriology
Publisher: American Society for Microbiology
Additional Information: Copy right of this article belongs to American Society for Microbiology.
Department/Centre: Division of Biological Sciences > Microbiology & Cell Biology
Date Deposited: 01 Sep 2009 07:07
Last Modified: 19 Sep 2010 05:43
URI: http://eprints.iisc.ac.in/id/eprint/22757

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