Fluorescent labelling of strychnine: A novel approach for recognition of strychnine binding sites on neuronal membrane

Bhattacharyya, PK and Bhattacharyya, Apares (1981) Fluorescent labelling of strychnine: A novel approach for recognition of strychnine binding sites on neuronal membrane. In: Biochemical and Biophysical Research Communications, 101 (1). pp. 273-280.

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Abstract

trychnine was coupled to fluorescein isothiocyanate to mark strychnine binding sites in spinal cord of rat. Specific binding of strychnine could be demonstrated in synaptosomal fraction. Addition of glycine to the strychninised membrane led to a decrease in fluorescence indicating same receptor loci.

Item Type:	Journal Article
Publication:	Biochemical and Biophysical Research Communications
Publisher:	Elsevier Science
Additional Information:	Copyright of this article belongs to Elsevier Science.
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	21 Jul 2009 14:34
Last Modified:	19 Sep 2010 05:34
URI:	http://eprints.iisc.ac.in/id/eprint/20800

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