Base specific binding of deoxyguanylate and deoxycytidylate antibodies to double stranded DNA

Jacob, Alexander and Jacob, TM (1982) Base specific binding of deoxyguanylate and deoxycytidylate antibodies to double stranded DNA. In: Nucleic Acids Research, 10 (20). pp. 6273-6280.

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Abstract

Antibodies raised in rabbits against daoxyguanylate and daoxycytidylate bind to 3H-(lambda) double stranded DNA and the binding is base specific. The concentrations of antibody populations that bind to double stranded DNA are much less than those binding to denatured DNA. Due to their low concentrations, these antibodies ware not detected in earlier studies. These antibodies are expected to be useful to probe the conformational flexibilities of double stranded DNAs.

Item Type:	Journal Article
Publication:	Nucleic Acids Research
Publisher:	Oxford University Press
Additional Information:	Copyright of this article belongs to Oxford University Press.
Department/Centre:	Division of Biological Sciences > Microbiology & Cell Biology
Date Deposited:	01 Jun 2009 08:58
Last Modified:	19 Sep 2010 05:32
URI:	http://eprints.iisc.ac.in/id/eprint/20398

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