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Heart rate variability as an index of cue reactivity in alcoholics

Rajan, I and Murthy, Naga Venkatesha PJ and Ramakrishnan, AG and Gangadhar, BN and Janakiramaiah, N (1998) Heart rate variability as an index of cue reactivity in alcoholics. In: Biological Psychiatry, 43 (07). pp. 544-546.


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Background: Autonomic responses follow exposure to conditioned stimuli such as contextual factors associated with alcohol ingestion. Heart rate variability is under autonomic control a,td may be a measure of such response. Methods: Twenty alcoholics and 23 matched social drinkers (all male) were exposed to a neutral cue and then an alcohol are in identical settings, during which the Electrocardiogram of these subjects was recorded, Time and frequency domain parameters of heart rate viability (HRV) were computed by a blind rater. Results: Coefficient of variation of R-R intervals and absolute powers of HRV spectrum (ill frequency bands 0.05-0.15 Hz and 0.01-0.05 Hz) following alcohol cue ,I ere significantly higher ill alcoholics than social drinkers. The mean heart rate (MHR) failed to reflect this difference. Conclusions: HRV paradigm appears more sensitive than MHR to measure cue reactivity. (C) 1998 Society of Biological Psychiatry.

Item Type: Journal Article
Publication: Biological Psychiatry
Publisher: Elsevier Science
Additional Information: Copyright of this article belongs to Elsevier Science.
Keywords: heart rate variability;alcohol dependence;cue reactivity.
Department/Centre: Division of Electrical Sciences > Electrical Engineering
Date Deposited: 23 Jul 2009 10:39
Last Modified: 19 Sep 2010 05:24
URI: http://eprints.iisc.ac.in/id/eprint/18688

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