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Size control in development: lessons from Drosophila

Kawli, Trupti S (2000) Size control in development: lessons from Drosophila. In: Journal of Biosciences, 25 (1). pp. 2-3.


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As long back as in 1927 J B S Haldane pointed out that “The most obvious differences between different animals are differences in size, but for some reason the zoologists have paid singularly little attention to them (Haldane 1927). Almost three quarters of a century later, one of the most important and fundamental aspects of development – how the size of a multicellular organism is determined – remains as mysterious as ever. The final size reached by an adult organism is a consequence of changes in the size and number of cells during its development. The critical factors thus are how many cells there are, how big a cell is on average and the amount of extracellular matrix and fluid present.

Item Type: Journal Article
Publication: Journal of Biosciences
Publisher: Indian Academy of Sciences
Additional Information: Copyright of this article belongs to Indian Academy of Sciences.
Department/Centre: Division of Biological Sciences > Molecular Reproduction, Development & Genetics
Date Deposited: 25 Aug 2008
Last Modified: 19 Sep 2010 04:15
URI: http://eprints.iisc.ac.in/id/eprint/1798

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