Band selective small flip angle COSY: A simple experiment for the analyses of H-1 NMR spectra of small chiral molecules

Prabhu, Uday Ramesh and Suryaprakash, N (2008) Band selective small flip angle COSY: A simple experiment for the analyses of H-1 NMR spectra of small chiral molecules. In: Journal of Magnetic Resonance, 195 (2). pp. 145-152.

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Abstract

The NMR spectroscopic discrimination of enantiomers in the chiral liquid crystalline solvent is more often carried out using 2H detection in its natural abundance. The employment of 1H detection for such a purpose is severely hampered due to significant loss of resolution in addition to indistinguishable overlap of the spectra from the two enantiomers. This study demonstrates that the band selected small flip angle homonuclear correlation experiment is a simple and robust technique that provides unambiguous discrimination, very high spectral resolution, reduced multiplicity of transitions, relative signs of the couplings and enormous saving of instrument time.

Item Type:	Journal Article
Publication:	Journal of Magnetic Resonance
Publisher:	Elsevier Science
Additional Information:	Copyright of this article belongs to Elsevier Science.
Keywords:	Band selective COSY;Small flip angle;Chiral discrimination; Couplings;Analyses of spectra.
Department/Centre:	Division of Chemical Sciences > Solid State & Structural Chemistry Unit Division of Chemical Sciences > NMR Research Centre (Formerly Sophisticated Instruments Facility)
Date Deposited:	04 May 2009 10:59
Last Modified:	19 Sep 2010 04:57
URI:	http://eprints.iisc.ac.in/id/eprint/17563

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