Srikrishna, A and Reddy, TJ and Kumar, PP and Gharpure, SJ (2001) Enantiospecific synthesis of B-seco-C-aromatic taxanes. In: Indian Journal Of Chemistry Section B-Organic Chemistry Including Medicinal Chemistry, 40 (10). pp. 905-914.
Full text not available from this repository. (Request a copy)
Official URL: http://www.niscair.res.in/ScienceCommunication/Res...
Abstract
A simple and efficient methodology for the enantiospecific synthesis of B-seco-C-aromatic taxanes starting from monoterpene (R)-carvone is described. Coupling of 6,6-dimethylcarvone 5 with appropriate arylethyl bromides followed by oxidation generates the enones 7, 15, 25, which are transformed into the 20-nor-B-seco-C-aromatic taxane derivatives 11, 17 and B-seco-C-aromatic taxane derivative 29 via degradation of the isopropenyl group.
| Item Type: | Journal Article |
|---|---|
| Publication: | Indian Journal Of Chemistry Section B-Organic Chemistry Including Medicinal Chemistry |
| Publisher: | National Institute of Science Communication and Information Resources |
| Additional Information: | Copyright of this article belongs to National Institute of Science Communication and Information Resources. |
| Keywords: | Stereocontrolled Synthesis;Baccatin-Iii;Ring-System;Pinene Path;Taxol;Chemistry. |
| Department/Centre: | Division of Chemical Sciences > Organic Chemistry |
| Date Deposited: | 03 Jun 2009 06:20 |
| Last Modified: | 03 Jun 2009 06:20 |
| URI: | http://eprints.iisc.ac.in/id/eprint/16890 |
Actions (login required)
 |
View Item |
