Sudhir, V Sai and Baig, Nasir RB and Chandrasekaran, Srinivasan (2008) Facile Entry to 4,5,6,7-Tetrahydro[1,2,3]triazolo[1,5-a]pyrazin-6-ones from Amines and Amino Acids. In: European Journal of Organic Chemistry (14). pp. 2423-2429.
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Official URL: http://www3.interscience.wiley.com/journal/1179475...
Abstract
A practical and high-yielding regioselective synthesis ofseveral enantiopure 4,5,6,7-tetrahydro[1,2,3]triazolo[1,5-a]pyrazin-6-ones is described starting from primary amines and -amino acid derivatives in a three-step reaction sequence by employing a constrained intramolecular click reaction as the key step. The method obviates chromatographic purification of products.
| Item Type: | Journal Article |
|---|---|
| Publication: | European Journal of Organic Chemistry |
| Publisher: | John Wiley and Sons |
| Additional Information: | Copyright belongs to John Wiley and Sons. |
| Keywords: | triazoles; alkynes; cycloaddition; nitrogen heterocycles; amino acids. |
| Department/Centre: | Division of Chemical Sciences > Organic Chemistry |
| Date Deposited: | 19 Jul 2009 08:24 |
| Last Modified: | 19 Sep 2010 04:54 |
| URI: | http://eprints.iisc.ac.in/id/eprint/16889 |
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