Vasudevachari, MB and Antony, A (1985) Antiviral activity of liposome-encapsulated cupric complex of isonicotinic acid hydrazide against avian myeloblastosis virus infection. In: Indian Journal of Experimental Biology, 23 (7). pp. 393-396.
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Cupric complex of isonicotinic acid hydrazide (cupric-INH complex) has been shown to inactivate avian myeloblastosis virus (AMV). The complex did not have any demonstrable chemotherapeutic activity against AMV infection in chicks. However, when encapsulated in positive charged liposomes the complex partially protected the chicks from AMV infection. The levels and stability of the complex in various tissues particularly in bone marrow, the target tissue for AMV multiplication, were higher in liposome-encapsulated cupric-INH complex injected than in chicks injected with unencapsulated complex.
| Item Type: | Journal Article |
|---|---|
| Publication: | Indian Journal of Experimental Biology |
| Publisher: | National Institute of Science Communication and Information Resources, |
| Additional Information: | Copyright of this article belongs to National Institute of Science Communication and Information Resources. |
| Department/Centre: | Division of Biological Sciences > Microbiology & Cell Biology |
| Date Deposited: | 11 Jul 2008 |
| Last Modified: | 27 Aug 2008 13:34 |
| URI: | http://eprints.iisc.ac.in/id/eprint/14971 |
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