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New model systems to study DNA-protein recognition mechanisms

Jacob, Alexander and Jacob, TM (1985) New model systems to study DNA-protein recognition mechanisms. In: FEBS Letters, 189 (1). pp. 81-84.

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dpG antibodies were fractionated on a cellulose-double-stranded DNA column. The flow-through fraction bound denatured DNA but not double-stranded DNA (dsDNA). The dpG-eluted fraction bound dsDNA preferentially. The results show that proteins can recognise dpG in DNA by different mechanisms, some involving DNA unwinding.

Item Type: Journal Article
Publication: FEBS Letters
Publisher: Elsevier
Additional Information: Copyright of this article belongs to Elsevier.
Department/Centre: Division of Biological Sciences > Biochemistry
Date Deposited: 08 Jul 2008
Last Modified: 19 Sep 2010 04:47
URI: http://eprints.iisc.ac.in/id/eprint/14853

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