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Effect of parthenin on mitochondrial oxidative phosphorylation

Narasimhan, TR and Harindranath, N and Kurup, CK and Rao, PV (1985) Effect of parthenin on mitochondrial oxidative phosphorylation. In: Biochemistry International, 11 (2). pp. 239-244.

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The sesquiterpene lactone, 'parthenin' the toxic principle of the allergenic weed Parthenium hysterophorus, inhibited 'state 3' respiration and stimulated 'state 4' respiration in rat liver and kidney mitochondria as well as ATPase activity in the presence of $Mg^{2+}$ ions. These properties indicate that the toxic action of parthenin may be related to its interference with oxidative phosphorylation.

Item Type: Journal Article
Publication: Biochemistry International
Publisher: Academic Press
Additional Information: Copyright of this article belongs to Academic Press.
Department/Centre: Division of Biological Sciences > Biochemistry
Date Deposited: 14 Jul 2008
Last Modified: 27 Aug 2008 13:31
URI: http://eprints.iisc.ac.in/id/eprint/14700

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