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The iron-binding properties of fermodulin

Devi, Usha S and Ramasarma, T (1987) The iron-binding properties of fermodulin. In: Indian Journal of Biochemistry & Biophysics, 24 (3). pp. 119-123.

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Fermodulin (I), the Fe-dependent inhibitor protein of rat liver microsomal hydroxymethylglutamyl-CoA reductase, is shown to interact with Fe. I had 1 specific site for $Fe^{2+}$ per mole, as determined by binding of radio labeled Fe and also by fluorescence quenching in a HEPES buffer system. In the presence of Tris buffer, however, 2 sites for binding Fe were observed 1 of which appeared to bind $Fe^{3+}$.

Item Type: Journal Article
Publication: Indian Journal of Biochemistry & Biophysics
Publisher: Council of Scientific & Industrial Research
Additional Information: Copyright of this article belongs to Council of Scientific & Industrial Research.
Department/Centre: Division of Biological Sciences > Biochemistry
Date Deposited: 20 Jun 2008
Last Modified: 27 Aug 2008 13:27
URI: http://eprints.iisc.ac.in/id/eprint/14355

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