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Interaction Profiling of T-Cell Epitopes with MHC-Class I Molecules

Dash, Banaja P and Mukherjee, Sumanto and Suhas, VL and Chandra, Nagasuma (2007) Interaction Profiling of T-Cell Epitopes with MHC-Class I Molecules. In: Protein and Peptide Letters, 14 (6). pp. 557-564.

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A key step in rational vaccine development is to understand how antigens are recognized by their receptors. Several crystal structures of MHC/HLA molecules are now available. We report a structural bioinformatics study of peptide- HLA complexes to derive features that generate recognition specificity, useful for guiding the design process.

Item Type: Journal Article
Publication: Protein and Peptide Letters
Publisher: Bentham Science Publishers
Additional Information: Copyright of this article belongs to Bentham Science Publishers.
Keywords: Epitope prediction;protein-peptide interaction;HLA class-I;vaccine design;structural bioinformatics
Department/Centre: Division of Information Sciences (Doesn't exist now) > BioInformatics Centre
Date Deposited: 05 Jun 2008
Last Modified: 27 Aug 2008 13:25
URI: http://eprints.iisc.ac.in/id/eprint/14206

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