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Genomic sequence of physalis mottle virus and its evolutionary relationship with other tymoviruses

Ranjith-Kumar, CT and Gopinath, K and Jacob, ANK and Srividhya, V and Elango, P and Savithri, HS (1998) Genomic sequence of physalis mottle virus and its evolutionary relationship with other tymoviruses. In: Archives of Virology, 143 (8). pp. 1489-1500.


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The genome of physalis mottle tymovirus (PhMV) is 6673 nucleotides long and is rich in cytosine residues (40.58%) like other tymoviruses. The organization of the genes is also similar to that of five other tymoviruses whose sequences are known. However, PhMV has the longest 3 0 noncoding region as well as the longest replicase (RP) ORF. The RP sequences are similar to those of other tymoviruses (48–60% identity) whereas the coat proteins (CP) and the overlapping proteins (OP) are conserved to a lesser extent (30–50% and 26–34% respectively). A tetra peptide GILG was found to be present in all the tymoviral OPs. The PhMV RP also possesses the methyl transferase, polymerase and the helicase motifs found in all the Sindbis-like super group of plant viruses. A phylogenetic analysis of the six tymoviral sequences revealed that they do not have a rigid hierarchical similarity relationship.

Item Type: Journal Article
Publication: Archives of Virology
Publisher: Springer-Verlag
Additional Information: Copyright for this article belongs to Springer-Verlag.
Department/Centre: Division of Information Sciences (Doesn't exist now) > BioInformatics Centre
Division of Biological Sciences > Biochemistry
Date Deposited: 25 Aug 2008
Last Modified: 19 Sep 2010 04:15
URI: http://eprints.iisc.ac.in/id/eprint/1414

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