Suryaprakash, N and Ramanathan, KV and Datta, Geeta and Gurnani, S and Khetrapal, CL (1984) Importance of sugar ring geometry in protein-nucleoside interactions. In: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 23 (12). pp. 1145-1147.
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The interaction of cytidine with lysozyme was studied by using NMR spectroscopy. The binding of the nucleoside affected the histidine-15 residue of lysozyme. An upfield shift of the proton resonance of the histidine-15 $C_2$-proton suggests stacking of the aromatic ring of cytidine over the histidine residue. The results indicate the importance of sugar geometry in the binding process.
| Item Type: | Journal Article |
|---|---|
| Publication: | Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry |
| Publisher: | National Institute of Science Communication and Information Resources, CSIR. |
| Additional Information: | Copyright of this article belongs to Council of Scientific & Industrial Research.National Institute of Science Communication and Information Resources, CSIR. |
| Department/Centre: | Division of Chemical Sciences > Sophisticated Instruments Facility (Continued as NMR Research Centre) |
| Date Deposited: | 12 May 2008 |
| Last Modified: | 27 Aug 2008 13:22 |
| URI: | http://eprints.iisc.ac.in/id/eprint/13932 |
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