Stereoselective Total Synthesis of (+)-Cardiobutanolide

Prasad, Kavirayani R and Gholap, Shivajirao L (2008) Stereoselective Total Synthesis of (+)-Cardiobutanolide. In: Journal of Organic Chemistry, 73 (7). 2916 -2919.

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Abstract

Stereoselective synthesis of styryllactone (+)-cardiobutanolide was accomplished in good overall yield from D-(-)-tartaric acid. Key features of the synthesis include the elaboration of a $\gamma$-hydroxy butyramide obtained from the dimethylamide of tartaric acid, involving a combination of the addition of 1,3-dithian-2-yllithium and stereoselective reduction.

Item Type:	Journal Article
Publication:	Journal of Organic Chemistry
Publisher:	American Chemical Society
Additional Information:	Copyright of this article belongs to American Chemical Society.
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	15 Apr 2008
Last Modified:	19 Sep 2010 04:44
URI:	http://eprints.iisc.ac.in/id/eprint/13742

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