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Control of transcription initiation

Nagaraja, V (1993) Control of transcription initiation. In: Journal of Biosciences, 18 (1). pp. 13-25.


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Mechanism of control of transcription initiation have expanded far beyond the classical operon concept. Control elements are multipartite and well separated from each other, The trans-factors bound to these sites make contacts with RNA polymerase: promoter complexes by DNA bending or looping to influence the initiation event. Activators and repressors are like two faces of the same coin and their function depends on the site of action, mode of interaction with DNA and also the nutritional status of the cell.

Item Type: Journal Article
Publication: Journal of Biosciences
Publisher: Indian Academy Sciences
Additional Information: Copyright for this article belongs to Indian Academy of Sciences.
Keywords: RNA polymerase;promoter;activator;repressor;transcription
Department/Centre: Division of Biological Sciences > Microbiology & Cell Biology
Date Deposited: 31 Aug 2004
Last Modified: 19 Sep 2010 04:14
URI: http://eprints.iisc.ac.in/id/eprint/1359

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