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Location of valinomycin in lipid vesicles

Sankaram, MB and Easwaran, KRK (1984) Location of valinomycin in lipid vesicles. In: Journal of Biosciences, 6 (5). pp. 635-642.


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The location of the cyclododecadepsipeptide, valinomycin in vesicles formed from two synthetic lipids is studied by differential scanning calorimetry, spin-label partitioning electron paramagnetic resonance and $[^1H]$-nuclear magnetic resonance. The results show that valinomycin is located near the head group region of dipalmitoyl phosphatidyl choline vesicles and in the hydrophobic core of the dimyristoyl phosphatidyl choline vesicles in the liquid crystalline phase.

Item Type: Journal Article
Publication: Journal of Biosciences
Publisher: Indian Academy of Sciences
Additional Information: Copyright of this article belongs to Indian Academy of Sciences.
Keywords: Valinomycin;dipalmitoylphosphatidylcholine;dimyristoylphosphatidylcholine;differential scanning calorimetry;electron spin resonance; nuclear magnetic resonance;ionophore-lipid interaction
Department/Centre: Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited: 24 Mar 2008
Last Modified: 19 Sep 2010 04:43
URI: http://eprints.iisc.ac.in/id/eprint/13433

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