Modulation of DNA methyltransferase during the life cycle of a mealybug Planococcus lilacinus

Devajyothi, C and Brahmachari, Vani (1989) Modulation of DNA methyltransferase during the life cycle of a mealybug Planococcus lilacinus. In: FEBS Letters, 250 (2). pp. 134-138.

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Abstract

The levels of de novo DNA methyltransferase were studied during the development of a mealybug, Planococcus lilacinus. No enzyme activity could be detected in extracts from second instar females. But the enzyme occurs at high levels in third instar females and is maintained at that level during fourth instar when gametogenesis, fertilization and chromosome imprinting occur. These results suggest a developmental stage-specific modulation of levels of DNA methyltransferase. Assays with synthetic polymers showed that the enzyme can methylate not only polymers containing GpG but also those containing CpA and CpI.

Item Type:	Journal Article
Publication:	FEBS Letters
Publisher:	Elsevier Science B.V.
Additional Information:	Copyright of this article belongs to Federation of European Biochemical Societies.
Keywords:	Chromosome imprinting;Fertilization;DNA methyltransferase;Sequence specificity;Synthetic polymer
Department/Centre:	Division of Biological Sciences > Microbiology & Cell Biology
Date Deposited:	13 Feb 2008
Last Modified:	19 Sep 2010 04:42
URI:	http://eprints.iisc.ac.in/id/eprint/12920

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