Synthesis of novel phosphatidylcholine lipids with fatty acid chains bearing aromatic units. Generation of oxidatively stable, fluid phospholipid membranes

Bhattacharya, Santanu and Subramanian, Marappan (2002) Synthesis of novel phosphatidylcholine lipids with fatty acid chains bearing aromatic units. Generation of oxidatively stable, fluid phospholipid membranes. In: Tetrahedron Letters, 43 (23). pp. 4203-4206.

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Abstract

The first examples of diacylphospholipid analogs, which contain aromatic units at various depths of their hydrocarbon chains, have been synthesized. The membranes produced from the sonicated aqueous suspensions of these newly synthesized lipids are oxidatively stable and possess long shelf life. These membranes maintain fluid character at ambient temperature making them ideal for membrane protein reconstitution studies.

Item Type:	Journal Article
Publication:	Tetrahedron Letters
Publisher:	Elsevier Science Ltd.
Additional Information:	Copyright of this article belongs to Elsevier Science Ltd.
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	01 Feb 2008
Last Modified:	19 Sep 2010 04:41
URI:	http://eprints.iisc.ac.in/id/eprint/12621

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