Enantiospecific total syntheses of (-)-valeranone

Srikrishna, A and Viswajanani, R and Dinesh, C (2004) Enantiospecific total syntheses of (-)-valeranone. In: Indian Journal of Chemistry, Section B: Organic Chemistry including Medicinal Chemistry, 43B (6). pp. 1265-1274.

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Abstract

Two convenient methodologies are described for the enantiospecific synthesis of (-)-valeranone. The hydrindanone I, obtained from the readily and abundantly available monoterpene (R)-carvone, was converted into the ketoaldehyde II via an alkene. In another direction the lactone III, obtained from the hydrindanone I, has been elaborated into the ketoaldehyde II employing two methodologies. Intramol. aldol condensation followed by hydrogenation transformed the ketoaldehyde II into (-)-valeranone.

Item Type:	Journal Article
Publication:	Indian Journal of Chemistry, Section B: Organic Chemistry including Medicinal Chemistry
Publisher:	National Institute of Science Communication
Additional Information:	The copyright belongs to National Institute of Science Communication
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	06 Nov 2007
Last Modified:	19 Sep 2010 04:41
URI:	http://eprints.iisc.ac.in/id/eprint/12385

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