An orphan gyrB in the Mycobacterium smegmatis genome uncovered by comparative genomics

Jain, P and Nagaraja, V (2002) An orphan gyrB in the Mycobacterium smegmatis genome uncovered by comparative genomics. In: Journal of Genetics, 81 (3). pp. 106-110.

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Abstract

DNA gyrase is an essential topoisomerase found in all bacteria. It is encoded by gyrB and gyrA genes. These genes are organized differently in different bacteria. Direct comparison of Mycobacterium tuberculosis and Mycobacterium smegmatis genomes reveals presence of an additional gyrB in M. smegmatis flanked by novel genes. Analysis of the amino acid sequence of GyrB from different organisms suggests that the orphan GyrB in M. smegmatis may have an important cellular role

Item Type:	Journal Article
Publication:	Journal of Genetics
Publisher:	Indian Academy of Sciences
Keywords:	Mycobacterium smegmatis;gyr genes;DNA gyrase;topoisomerase;comparative genomics
Department/Centre:	Division of Biological Sciences > Microbiology & Cell Biology
Date Deposited:	17 Dec 2004
Last Modified:	19 Sep 2010 04:14
URI:	http://eprints.iisc.ac.in/id/eprint/1116

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