Design and Synthesis of Novel Chiral Dendritic Species Derived from Bile Acids

Balasubramanian, R and Maitra, Uday (2001) Design and Synthesis of Novel Chiral Dendritic Species Derived from Bile Acids. In: Journal Organic Chemistry, 66 (9). pp. 3035-3040.

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Abstract

Bile acids have been used for the first time as the building block for the construction of dendritic units. Orthogonally functionalized 7-deoxycholic and cholic acid derivatives were synthesized. The construction of a bile acid heptamer, a nonamer, and a decamer using the convergent strategy are described in detail. Chromatographic, spectral, and optical properties of these molecules have been investigated. Molecular modeling suggests that these molecules have globular shapes with nanometric dimensions.

Item Type:	Journal Article
Publication:	Journal Organic Chemistry
Publisher:	American Chemical Society
Additional Information:	Copyright of this article belongs to American Chemical Society.
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	16 Apr 2007
Last Modified:	19 Sep 2010 04:37
URI:	http://eprints.iisc.ac.in/id/eprint/10634

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