Differential binding of RNA polymerase to the wild type Mu mom promoter and its C independent mutant: a theoretical analysis

Nair, Murlidharan T and Kulkarni, BD and Nagaraja, V (1995) Differential binding of RNA polymerase to the wild type Mu mom promoter and its C independent mutant: a theoretical analysis. In: Biophysical Chemistry, 53 (3). pp. 241-245.

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Abstract

Using the theoretical model for DNA bending we have analyzed the Mu mom promoter wild type and its mutant tin7 which showed differential binding to the RNA polymerase.We have demonstrated here the structural change as a result of the point mutation which may be responsible for the altered binding of RNA polymerase. Analysis using both sets of parameters essentially gives the same result.

Item Type:	Journal Article
Publication:	Biophysical Chemistry
Publisher:	Elsevier
Keywords:	DNA curvature;Promoter structure;RNA polymerase
Department/Centre:	Division of Biological Sciences > Microbiology & Cell Biology
Date Deposited:	09 Dec 2004
Last Modified:	19 Sep 2010 04:13
URI:	http://eprints.iisc.ac.in/id/eprint/1016

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