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Guanacastepene-A total synthesis: construction of the tricyclic iso-guanacastepane, epi-guanacastepane and guanacastepane frameworks

Mehta, Goverdhan and Umarye, Jayant D and Srinivas, Kalidindi (2003) Guanacastepene-A total synthesis: construction of the tricyclic iso-guanacastepane, epi-guanacastepane and guanacastepane frameworks. In: Tetrahedron Letters, 44 (22). pp. 4233-4237.

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Abstract

Studies aimed towards the total synthesis of the diterpene antibiotic, guanacastepene A, of current interest and displaying promising biological activity against drug resistant pathogens has led to the generation of some novel tricyclic skeleta replete with extensive functionalization and representing interesting variations of the guanacastepane framework.

Item Type: Journal Article
Publication: Tetrahedron Letters
Publisher: Elsevier Science
Additional Information: Copyright for this article belongs to Elsevier Science.
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Date Deposited: 12 Jul 2004
Last Modified: 19 Sep 2010 04:13
URI: http://eprints.iisc.ac.in/id/eprint/1001

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