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Journal Article

Thakur, M and Muniyappa, K (2023) Global genome and transcription-coupled nucleotide excision repair pathway in prokaryotes. In: Journal of Biosciences, 48 (4).

Somashekara, SC and Dhyani, KM and Thakur, M and Muniyappa, K (2023) SUMOylation of yeast Pso2 enhances its translocation and accumulation in the mitochondria and suppresses methyl methanesulfonate-induced mitochondrial DNA damage. In: Molecular Microbiology, 120 (4). pp. 477-628.

Somashekara, SC and Dhyani, KM and Thakur, M and Muniyappa, K (2023) SUMOylation of yeast Pso2 enhances its translocation and accumulation in the mitochondria and suppresses methyl methanesulfonate-induced mitochondrial DNA damage. In: Molecular Microbiology, 120 (4). pp. 587-607.

Biswas, S and Basak, S and Samui, S and Pasadi, S and Muniyappa, K and Naskar, J (2023) Co-Assembly of Peptide with G-Quadruplex DNA: A Strategic Approach to Develop Anticancer Therapeutics. In: ChemistrySelect, 8 (7).

Thakur, M and Muniyappa, K (2023) Macrophage activation highlight an important role for NER proteins in the survival, latency and multiplication of Mycobacterium tuberculosis. In: Tuberculosis, 138 .

Roy, S and Chakraborty, N and Maiti, B and Muniyappa, K and Bhattacharya, S (2022) Design and Synthesis of Xanthone Analogues Conjugated with Aza-aromatic Substituents as Promising G-Quadruplex Stabilizing Ligands and their Selective Cancer Cell Cytotoxic Action. In: ChemBioChem .

Roy, S and Muniyappa, K and Bhattacharya, S (2022) Deciphering the Binding Insights of Novel Disubstituted Anthraquinone Derivatives with G-Quadruplex DNA to Exhibit Selective Cancer Cell Cytotoxicity. In: ChemMedChem .

Thakur, M and Parulekar, RS and Barale, SS and Sonawane, KD and Muniyappa, K (2022) Interrogating the substrate specificity landscape of UvrC reveals novel insights into its non-canonical function. In: Biophysical Journal .

Somashekara, SC and Muniyappa, K (2022) Dual targeting of Saccharomyces cerevisiae Pso2 to mitochondria and the nucleus, and its functional relevance in the repair of DNA interstrand crosslinks. In: G3: Genes, Genomes, Genetics, 12 (6).

Roy, S and Maiti, B and Banerjee, N and Kaulage, MH and Muniyappa, K and Chatterjee, S and Bhattacharya, S (2022) New Xanthone Derivatives as Potent G-Quadruplex Binders for Developing Anti-Cancer Therapeutics. In: ACS Pharmacology and Translational Science .

Thakur, M and Mohan, D and Singh, AK and Agarwal, A and Gopal, B and Muniyappa, K (2021) Novel insights into ATP-Stimulated Cleavage of branched DNA and RNA Substrates through Structure-Guided Studies of the Holliday Junction Resolvase RuvX. In: Journal of Molecular Biology, 433 (13).

Majee, P and Kumar Mishra, S and Pandya, N and Shankar, U and Pasadi, S and Muniyappa, K and Nayak, D and Kumar, A (2020) Identification and characterization of two conserved G-quadruplex forming motifs in the Nipah virus genome and their interaction with G-quadruplex specific ligands. In: Scientific Reports, 10 (1).

Pasadi, S and Muniyappa, K (2020) Evidence for functional and regulatory cross-talk between Wnt/ β-catenin signalling and Mre11–Rad50–Nbs1 complex in the repair of cisplatin-induced DNA cross-links. In: Oncotarget, 11 (44). pp. 4028-4044.

Prasad, D and Muniyappa, K (2020) The extended N-terminus of Mycobacterium smegmatis RecX potentiates its ability to antagonize RecA functions. In: Biochimica et Biophysica Acta - Proteins and Proteomics, 1868 (10).

Biswas, S and Samui, S and Das, AK and Pasadi, S and Muniyappa, K and Naskar, J (2020) Targeting G-quadruplex DNA with synthetic dendritic peptide: Modulation of the proliferation of human cancer cells. In: RSC Advances, 10 (44). pp. 26388-26396.

Majee, P and Shankar, U and Pasadi, S and Muniyappa, K and Nayak, D and Kumar, A (2020) Genome-wide analysis reveals a regulatory role for G-quadruplexes during Adenovirus multiplication. In: Virus Research, 283 .

Thakur, M and Agarwal, A and Muniyappa, K (2020) The intrinsic ATPase activity of Mycobacterium tuberculosis UvrC is crucial for its damage-specific DNA incision function. In: FEBS Journal, 288 (4). pp. 1179-1200.

Roy, S and Ali, A and Kamra, M and Muniyappa, K and Bhattacharya, S (2020) Specific stabilization of promoter G-Quadruplex DNA by 2,6-disubstituted amidoanthracene-9,10-dione based dimeric distamycin analogues and their selective cancer cell cytotoxicity. In: European Journal of Medicinal Chemistry, 195 .

Thakur, M and Muniyappa, K (2020) Deciphering the essentiality and function of SxSx motif in Mycobacterium tuberculosis UvrB. In: Biochimie, 170 . pp. 94-105.

Prasad, Deepika and Arora, Divya and Nandicoori, Vinay Kumar and Muniyappa, K (2019) Elucidating the functional role of Mycobacterium smegmatis recX in stress response. In: SCIENTIFIC REPORTS, 9 .

Prasad, D and Muniyappa, K (2019) The anionic phospholipids in the plasma membrane play an important role in regulating the biochemical properties and biological functions of RecA proteins. In: Biochemistry .

Manikandan, Kasi and Prasad, Deepika and Srivastava, Ankita and Singh, Nirpendra and Dabeer, Sadaf and Krishnan, Anuja and Muniyappa, K and Sinha, Krishna Murari (2018) The second messenger cyclic di-AMP negatively regulates the expression of Mycobacterium smegmatis recA and attenuates DNA strand exchange through binding to the C-terminal motif of mycobacterial RecA proteins. In: MOLECULAR MICROBIOLOGY, 109 (5). pp. 600-614.

Sharadamma, Narayanaswamy and Harshavardhana, Yadumurthy and Muniyappa, K (2018) Defining the Functionally Important Domain and Amino Acid Residues in Mycobacterium tuberculosis Integration Host Factor for Genome Stability, DNA Binding, and Integrative Recombination (vol 199, e00357-17, 2017). In: JOURNAL OF BACTERIOLOGY, 200 (9).

Kaulage, Mangesh H and Bhattacharya, Santanu and Muniyappa, K (2018) Structural Characterization of i-Motif Structure in the Human Acetyl-CoA Carboxylase1 Gene Promoters and Their Role in the Regulation of Gene Expression. In: CHEMBIOCHEM, 19 (10). pp. 1078-1087.

Kaulage, Mangesh H and Maji, Basudeb and Pasadi, Sanjeev and Ali, Asfa and Bhattacharya, Santanu and Muniyappa, K (2018) Targeting G-quadruplex DNA structures in the telomere and oncogene Promoter regions by benzimidazole-carbazole ligands. In: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 148 . pp. 178-194.

Sharadamma, Narayanaswamy and Harshavardhana, Yadumurthy and Muniyappa, K (2017) Defining the Functionally Important Domain and Amino Acid Residues in Mycobacterium tuberculosis Integration Host Factor for Genome Stability, DNA Binding, and Integrative Recombination. In: JOURNAL OF BACTERIOLOGY, 199 (19).

Ali, Asfa and Kamra, Mohini and Roy, Soma and Muniyappa, K and Bhattacharya, Santanu (2017) Enhanced G-Quadruplex DNA Stabilization and Telomerase Inhibition by Novel Fluorescein Derived Salen and Salphen Based Ni(II) and Pd(II) Complexes. In: BIOCONJUGATE CHEMISTRY, 28 (2). pp. 341-352.

Kaulage, Mangesh H and Maji, Basudeb and Pasadi, Sanjeev and Bhattacharya, Santanu and Muniyappa, K (2017) Novel ruthenium azo-quinoline complexes with enhanced photonuclease activity in human cancer cells. In: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 139 . pp. 1016-1029.

Kshirsagar, Rucha and Khan, Krishnendu and Joshi, Mamata V and Hosur, Ramakrishna V and Muniyappa, K (2017) Probing the Potential Role of Non-B DNA Structures at Yeast Meiosis-Specific DNA Double-Strand Breaks. In: BIOPHYSICAL JOURNAL, 112 (10). pp. 2056-2074.

Kshirsagar, Rucha and Ghodke, Indrajeet and Muniyappa, K (2017) Saccharomyces cerevisiae Red1 protein exhibits nonhomologous DNA end-joining activity and potentiates Hop1-promoted pairing of double-stranded DNA. In: JOURNAL OF BIOLOGICAL CHEMISTRY, 292 (33). pp. 13853-13866.

Kaulage, Mangesh and Maji, Basudeb and Bhat, Jyotsna and Iwasaki, Yasumasa and Chatterjee, Subhrangsu and Bhattacharya, Santanu and Muniyappa, K (2016) Discovery and Structural Characterization of G-quadruplex DNA in Human Acetyl-CoA Carboxylase Gene Promoters: Its Role in Transcriptional Regulation and as a Therapeutic Target for Human Disease. In: JOURNAL OF MEDICINAL CHEMISTRY, 59 (10). pp. 5035-5050.

Ujaoney, Aman K and Basu, Bhakti and Muniyappa, K and Apte, Shree K (2016) Functional roles of N-terminal and C-terminal domains in the overall activity of a novel single-stranded DNA binding protein of Deinococcus radiodurans. In: FEBS OPEN BIO, 5 . pp. 378-387.

Ghodke, Indrajeet and Muniyappa, K (2016) Genetic and biochemical evidences reveal novel insights into the mechanism underlying Saccharomyces cerevisiae Sae2-mediated abrogation of DNA replication stress. In: JOURNAL OF BIOSCIENCES, 41 (4). pp. 615-641.

Manjunath, GP and Soni, Neelesh and Vaddavalli, Pavana L and Shewale, Dipeshwari J and Madhusudhan, MS and Muniyappa, K (2016) Molecular Mechanism Underlying ATP-Induced Conformational Changes in the Nucleoprotein Filament of Mycobacterium smegmatis RecA. In: BIOCHEMISTRY, 55 (12). pp. 1850-1862.

Nautiyal, Astha and Rani, Sandhya P and Sharples, Gary J and Muniyappa, K (2016) Mycobacterium tuberculosis RuvX is a Holliday junction resolvase formed by dimerisation of the monomeric YqgF nuclease domain. In: MOLECULAR MICROBIOLOGY, 100 (4). pp. 656-674.

Nautiyal, Astha and Rani, Sandhya P and Sharples, Gary J and Muniyappa, K (2016) Mycobacterium tuberculosis RuvX is a Holliday junction resolvase formed by dimerisation of the monomeric YqgF nuclease domain (vol 100, pg 656, 2016). In: MOLECULAR MICROBIOLOGY, 101 (1). p. 182.

Thakur, Manoj and Kumar, Mohan BJ and Muniyappa, K (2016) Mycobacterium tuberculosis UvrB Is a Robust DNA-Stimulated ATPase That Also Possesses Structure-Specific ATP-Dependent DNA Helicase Activity. In: BIOCHEMISTRY, 55 (41). pp. 5865-5883.

Ali, Asfa and Kamra, Mohini and Roy, Soma and Muniyappa, K and Bhattacharya, Santanu (2016) Novel Oligopyrrole Carboxamide based Nickel(II) and Palladium(II) Salens, Their Targeting of Human G-Quadruplex DNA, and Selective Cancer Cell Toxicity. In: CHEMISTRY-AN ASIAN JOURNAL, 11 (18). pp. 2542-2554.

Sharadamma, Narayanaswamy and Harshavardhana, Yadumurthy and Ravishankar, Apoorva and Anand, Praveen and Chandra, Nagasuma and Muniyappa, K (2015) Molecular Dissection of Mycobacterium tuberculosis Integration Host Factor Reveals Novel Insights into the Mode of DNA Binding and Nucleoid Compaction. In: BIOCHEMISTRY, 54 (26). pp. 4142-4160.

Dewhare, Shivendra Singh and Umesh, TG and Muniyappa, K (2015) Molecular and Functional Characterization of RecD, a Novel Member of the SF1 Family of Helicases, from Mycobacterium tuberculosis. In: JOURNAL OF BIOLOGICAL CHEMISTRY, 290 (19). pp. 11948-11968.

Thakur, Roshan Singh and Basavaraju, Shivakumar and Khanduja, Jasbeer Singh and Muniyappa, K and Nagaraju, Ganesh (2015) Mycobacterium tuberculosis RecG Protein but Not RuvAB or RecA Protein Is Efficient at Remodeling the Stalled Replication Forks IMPLICATIONS FOR MULTIPLE MECHANISMS OF REPLICATION RESTART IN MYCOBACTERIA. In: JOURNAL OF BIOLOGICAL CHEMISTRY, 290 (40). pp. 24119-24139.

Maji, Basudeb and Kumar, Krishan and Muniyappa, K and Bhattacharya, Santanu (2015) New dimeric carbazole-benzimidazole mixed ligands for the stabilization of human telomeric G-quadruplex DNA and as telomerase inhibitors. A remarkable influence of the spacer. In: ORGANIC & BIOMOLECULAR CHEMISTRY, 13 (30). pp. 8335-8348.

Chandran, Anu V and Prabu, Rajan J and Nautiyal, Astha and Patil, Neelakanteshwar K and Muniyappa, K and Vijayan, M (2015) Structural studies on Mycobacterium tuberculosis RecA: Molecular plasticity and interspecies variability. In: JOURNAL OF BIOSCIENCES, 40 (1). pp. 13-30.

Maji, Basudeb and Kumar, Krishan and Kaulage, Mangesh and Muniyappa, K and Bhattacharya, Santanu (2014) Design and Synthesis of New Benzimidazole-Carbazole Conjugates for the Stabilization of Human Telomeric DNA, Telomerase Inhibition, and Their Selective Action on Cancer Cells. In: JOURNAL OF MEDICINAL CHEMISTRY, 57 (16). pp. 6973-6988.

Muniyappa, K and Kshirsagar, Rucha and Ghodke, Indrajeet (2014) The HORMA domain: an evolutionarily conserved domain discovered in chromatin-associated proteins, has unanticipated diverse functions. In: GENE, 545 (2). pp. 194-197.

Sharadamma, Narayanaswamy and Harshavardhana, Yadumurthy and Ravishankar, Apoorva and Anand, Praveen and Chandra, Nagasuma and Muniyappa, K (2014) Molecular Dissection of Mycobacterium tuberculosis Integration Host Factor Reveals Novel Insights into the Mode of DNA Binding and Nucleoid Compaction. In: JOURNAL OF BIOLOGICAL CHEMISTRY, 289 (49). pp. 34325-34340.

Gupta, Shruti and De, Siddharth and Srivastava, Vivek and Hussain, Mansoor and Kumari, Jyoti and Muniyappa, K and Sengupta, Sagar (2014) RECQL4 and p53 potentiate the activity of polymerase and maintain the integrity of the human mitochondrial genome. In: CARCINOGENESIS, 35 (1). pp. 34-45.

Nautiyal, Astha and Patil, Neelakanteshwar K and Muniyappa, K (2014) Suramin is a potent and selective inhibitor of Mycobacterium tuberculosis RecA protein and the SOS response: RecA as a potential target for antibacterial drug discovery. In: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 69 (7). pp. 1834-1843.

Khan, Krishnendu and Madhavan, Vipin TP and Kshirsagar, Rucha and Boosi, Kannan N and Sadhale, Parag and Muniyappa, K (2013) N-Terminal disordered domain of saccharomyces cerevisiae Hop1 protein Is dispensable for DNA binding, bridging, and synapsis of double-stranded DNA molecules but is ecessary for spore formation. In: Biochemistry, 52 (31). pp. 5265-5279.

Ghodke, Indrajeet and Muniyappa, K (2013) Processing of DNA double-stranded breaks and intermediates of recombination and repair by saccharomyces cerevisiae Mre11 and its stimulation by Rad50, Xrs2, and Sae2 proteins. In: Journal of Biological Chemistry, 288 (16). pp. 11273-11286.

Fu, Hongxia and Le, Shimin and Chen, Hu and Muniyappa, K and Yan, Jie (2013) Force and ATP hydrolysis dependent regulation of RecA nucleoprotein filament by single-stranded DNA binding protein. In: NUCLEIC ACIDS RESEARCH, 41 (2). pp. 924-932.

Khan, Krishnendu and Madhavan, Vipin TP and Kshirsagar, Rucha and Boosi, Kannan N and Sadhale, Parag and Muniyappa, K (2013) N-Terminal Disordered Domain of Saccharomyces cerevisiae Hop1 Protein Is Dispensable for DNA Binding, Bridging, and Synapsis of Double-Stranded DNA Molecules But Is Necessary for Spore Formation. In: BIOCHEMISTRY, 52 (31). pp. 5265-5279.

Paul, Ananya and Jain, AkashK and Misra, SantoshK and Maji, Basudeb and Muniyappa, K and Bhattacharya, Santanu (2012) Binding of Gemini Bisbenzimidazole Drugs with Human Telomeric G-Quadruplex Dimers: Effect of the Spacer in the Design of Potent Telomerase Inhibitors. In: PLOS ONE, 7 (6).

Jain, Akash K and Paul, Ananya and Maji, Basudeb and Muniyappa, K and Bhattacharya, Santanu (2012) Dimeric 1,3-Phenylene-bis(piperazinyl benzimidazole)s: Synthesis and Structure-Activity Investigations on their Binding with Human Telomeric G-Quadruplex DNA and Telomerase Inhibition Properties. In: Journal of Medicinal Chemistry, 55 (7). pp. 2981-2993.

Khanduja, Jasbeer S and Muniyappa, K (2012) Functional Analysis of DNA Replication Fork Reversal Catalyzed by Mycobacterium tuberculosis RuvAB Proteins. In: Journal of Biological Chemistry, 287 (2). pp. 1345-1360.

Khan, Krishnendu and Karthikeyan, Usha and Li, You and Yan, Jie and Muniyappa, K (2012) Single-Molecule DNA Analysis Reveals That Yeast Hop1 Protein Promotes DNA Folding and Synapsis: Implications for Condensation of Meiotic Chromosomes. In: ACS NANO, 6 (12). pp. 10658-10666.

Paul, Ananya and Maji, Basudeb and Misra, Santosh K and Jain, Akash K and Muniyappa, K and Bhattacharya, Santanu (2012) Stabilization and Structural Alteration of the G-Quadruplex DNA Made from the Human Telomeric Repeat Mediated by Troger's Base Based Novel Benzimidazole Derivatives. In: JOURNAL OF MEDICINAL CHEMISTRY, 55 (17). pp. 7460-7471.

Patil, Neelakanteshwar K and Singh, Pawan and Harsha, Sri and Muniyappa, K (2011) Mycobacterium leprae RecA is structurally analogous but functionally distinct from Mycobacterium tuberculosis RecA protein. In: Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, 1814 (12). pp. 1802-1811.

Sharadamma, N and Khan, Krishnendu and Kumar, Sandeep and Patil, Neelakanteshwar K and Hasnain, Seyed E and Muniyappa, K (2011) Synergy between the N-terminal and C-terminal domains of Mycobacterium tuberculosis HupB is essential for high-affinity binding, DNA supercoiling and inhibition of RecA-promoted strand exchange. In: FEBS Journal, 278 (18). pp. 3447-3462.

Rossi, Franca and Khanduja, Jasbeer Singh and Bortoluzzi, Alessio and Houghton, Joanna and Sander, Peter and Guethlein, Carolin and Davis, Elaine O and Springer, Burkhard and Boettger, Erik C and Relini, Annalisa and Penco, Amanda and Muniyappa, K and Rizzi, Menico (2011) The biological and structural characterization of Mycobacterium tuberculosis UvrA provides novel insights into its mechanism of action. In: Nucleic Acids Research, 39 (16). pp. 7316-7328.

Patil, Neelakanteshwar K and Singh, Pawan and Muniyappa, K (2011) DNA Binding, Coprotease, and Strand Exchange Activities of Mycobacterial RecA Proteins: Implications for Functional Diversity among RecA Nucleoprotein Filaments. In: Biochemistry, 50 (2). pp. 300-311.

Kavitha, CV and Choudhary, Bibha and Raghavan, Sathees C and Muniyappa, K (2010) Differential regulation of MRN (Mre11-Rad50-Nbs1) complex subunits and telomerase activity in cancer cells. In: Biochemical and Biophysical Research Communications, 399 (4). pp. 575-580.

Chandran, Anu V and Prabu, J Rajan and Manjunath, GP and Patil, Neelakanteshwar K and Muniyappa, K and Vijayan, M (2010) Crystallization and preliminary X-ray studies of the C-terminal domain of Mycobacterium tuberculosis LexA. In: Acta Crystallographica Section F, 66 (Part 9). pp. 1093-1095.

Khan, Krishnendu and Madhavan, TP Vipin and Muniyappa, K (2010) Cloning,overexpression and purification of functionally active Saccharomyces cerevisiae Hop1 protein from scherichia coli. In: Protein Expression and Purification, 72 (1). pp. 42-47.

Singh, P and Neelakanteshwar, K and Khanduja, JS and Kumar, PS and Williams, A and Rossi, F and Rizzi, M and Davis, EO and Muniyappa, K (2010) Mycobacterium tuberculosis UvrD1 and UvrA Proteins Suppress DNA Strand Exchange Promoted by Cognate and Noncognate RecA Proteins. In: Biochemistry, 49 (23). pp. 4872-4883.

Singh, P and Neelakanteshwar, K and Khanduja, JS and Kumar, PS and Williams, A and Rossi, F and Rizzi, M and Davis, EO and Muniyappa, K (2010) Mycobacterium tuberculosis UvrD1 and UvrA Proteins Suppress DNA Strand Exchange Promoted by Cognate and Noncognate RecA Proteins. In: Biochemistry, 49 (23). pp. 4872-4883.

Sharadamma, N and Harshavardhana, Y and Singh, Pawan and Muniyappa, K (2010) Mycobacterium tuberculosis nucleoid-associated DNA-binding protein H-NS binds with high-affinity to the Holliday junction and inhibits strand exchange promoted by RecA protein. In: Nucleic Acids Research, 38 (11). pp. 3555-3569.

Singh, Pawan and Tripathi, Pankaj and Muniyappa, K (2010) Mutational analysis of active-site residues in the Mycobacterium leprae RecA intein, a LAGLIDADG homing endonuclease: Asp(122) and Asp(193) are crucial to the double-stranded DNA cleavage activity whereas Asp(218) is not. In: Protein Science, 19 (1). pp. 111-123.

Jain, Akash K and Reddy, Vishnu Vardhan and Paul, Ananya and Muniyappa, K and Bhattacharya, Santanu (2009) Synthesis and Evaluation of a Novel Class of G-Quadruplex-Stabilizing Small Molecules Based on the 1,3-Phenylene-Bis(piperazinyl benzimidazole) System. In: Biochemistry, 48 (45). pp. 10693-10704.

Singh, Pawan and Tripathi, Pankaj and Silva, George and Pingoud, Alfred and Muniyappa, K (2009) Characterization of Mycobacterium leprae RecA intein, a LAGLIDADG homing endonuclease, reveals a unique mode of DNA-binding, helical distortion and cleavage, compared to a canonical LAGLIDADG homing endonuclease. In: Journal of Biological Chemistry, 284 . pp. 25912-25928.

Prabu, J Rajan and Thamotharan, S and Khanduja, Jasbeer Singh and Chandra, Nagasuma R and Muniyappa, K and Vijayan, M (2009) Crystallographic and modelling studies on Mycobacterium tuberculosis RuvA: Additional role of RuvB-binding domain and inter species variability. In: Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics, 1794 (7). pp. 1001-1009.

Kavitha, CV and Nambiar, Mridula and Kumar, Ananda CS and Choudhary, Bibha and Muniyappa, K and Rangappa, Kanchugarakoppal S. and Raghavan, Sathees C (2009) Novel derivatives of spirohydantoin induce growth inhibition followed by apoptosis in leukemia cells. In: Biochemical Pharmacology, 77 (3). pp. 348-363.

Khanduja, Jasbeer Singh and Tripathi, Pankaj and Muniyappa, K (2009) Mycobacterium tuberculosis RuvA Induces Two Distinct Types of Structural Distortions between the Homologous and Heterologous Holliday Junctions. In: Biochemistry, 48 (01). pp. 27-40.

Prabu, Rajan J and Manjunath, GP and Chandra, Nagasuma R and Muniyappa, K and Vijayan, M (2008) Functionally important movements in RecA molecules and filaments: studies involving mutation and environmental changes. In: Acta Crystallographica Section D - Biological Crystallography, 64 (Part 1). pp. 1146-1157.

Tripathi, Pankaj and Pal, Debnath and Muniyappa, K (2007) Saccharomyces cerevisiae Hop1 Protein Zinc Finger Motif Binds to the Holliday Junction and Distorts the DNA Structure: Implications for Holliday Junction. In: Biochemistry, 46 (44). pp. 12530-12542.

Ghosal, Gargi and Muniyappa, K (2007) The Characterization of Saccharomyces cerevisiae Mre11/Rad50/Xrs2 Complex Reveals that Rad50 Negatively Regulates Mre11 Endonucleolytic but not the Exonucleolytic Activity. In: Journal of Molecular Biology, 372 (4). pp. 864-882.

Krishna, R and Prabu, Rajan J and Manjunath, GP and Datta, S and Chandra, NR and Muniyappa, K and Vijayan, M (2007) Snapshots of RecA Protein Involving Movement of the C-domain and Different Conformations of the DNA-binding Loops: Crystallographic and Comparative Analysis of 11 Structures of Mycobacterium smegmatis RecA. In: Journal of Molecular Biology, 367 (4). pp. 1130-1144.

Muniyappa, K (2007) The role of postdoctoral training for careers in research and higher education. In: Current Science, 92 (4). pp. 450-454.

Tripathi, Pankaj and Anuradha, S and Ghosal, Gargi and Muniyappa, K (2006) Selective Binding of Meiosis-specific Yeast Hop1 Protein to the Holliday Junctions Distorts the DNA Structure and Its Implications for Junction Migration and Resolution. In: Journal of Molecular Biology, 364 (4). pp. 599-611.

Muniyappa, K (2006) Competition among academic institutions. In: Current Science, 91 (5). pp. 565-566.

Prabu, J Rajan and Thamotharan, S and Khanduja, Jasbeer Singh and Alipio, Emily Zabala and Kim, Chang-Yub and Waldo, Geoffrey S and Terwilliger, Thomas C and Segelke, Brent and Lekin, Tim and Toppani, Dominique and Hung, Li-Wei and Yu, Minmin and Bursey, Evan Bursey and Muniyappa, K and Chandra, Nagasuma R and Vijayan, M (2006) Structure of Mycobacterium tuberculosis RuvA, a protein involved in recombination. In: Acta Crystallogr Sect F Struct Biol Cryst Commun, 62 (8). 731 -734.

Ghosal, Gargi and Muniyappa, K (2006) Hoogsteen base-pairing revisited: Resolving a role in normal biological processes and human diseases. In: Biochemical and Biophysical Research Communications, 343 (1). pp. 1-7.

Krishna, R and Manjunath, GP and Kumar, P and Surolia, A and Nagasuma, Chandra R and Muniyappa, K and Vijayan, M (2006) Crystallographic identification of an ordered C-terminal domain and a second nucleotide-binding site in RecA: new insights into allostery. In: Nucleic Acids Research, 34 (9). 2186-2195.

Anuradha, S and Tripathi, Pankaj and Mahajan, Kiran and Muniyappa, K (2005) Meiosis-specific yeast Hop1 protein promotes pairing of double-stranded DNA helices via G/C isochores. In: Biochemical and Biophysical Research Communications, 336 (3). pp. 934-941.

Anuradha, S and Muniyappa, K (2005) Molecular Aspects of Meiotic Chromosome Synapsis and Recombination. In: Progress in Nucleic Acid Research and Molecular Biology, 79 . pp. 49-132.

Saikrishnan, K and Manjunath, GP and Singh, Pawan and Jeyakanthan, J and Dauter, Z and Sekar, K and Muniyappa, K and Vijayan, M (2005) Structure of Mycobacterium smegmatis single-stranded DNA-binding protein and a comparative study involving homologus SSBs: biological implications of structural plasticity and variability in quaternary association. In: Acta Crystallographica Section D: Biological Crystallography, 61 . pp. 1140-1148.

Ghosal, Gargi and Muniyappa, K (2005) Saccharomyces cerevisiae Mre11 is a high-affinity G4 DNA-binding protein and a G-rich DNA-specific endonuclease: implications for replication of telomeric DNA. In: Nucleic Acids Research, 33 (15). pp. 4692-4703.

Anuradha, S and Muniyappa, K (2004) Saccharomyces cerevisiae Hop1 Zinc Finger Motif Is the Minimal Region Required for Its Function in Vitro. In: Journal of Biological Chemistry, 279 (28). pp. 28961-28969.

Anuradha, S and Muniyappa, K (2004) Meiosis-specific yeast Hop1 protein promotes synapsis of double-stranded DNA helices via the formation of guanine quartets. In: Nucleic Acids Research, 32 (8). pp. 2378-2385.

Muniyappa, K and Ganesh, N and Guhan, N and Singh, Pawan and Manjunath, GP and Datta, S and Chandra, Nagasuma R and Vijayan, M (2004) Homologous recombination in mycobacteria. In: Current Science, 86 (1). pp. 141-148.

Datta, S and Krishna, R and Ganesh, N and Chandra, Nagasuma R and Muniyappa, K and Vijayan, M (2003) Crystal Structures of Mycobacterium smegmatis RecA and Its Nucleotide Complexes. In: Journal of Bacteriology, 185 . pp. 4280-4284.

Guhan, N and Muniyappa, K (2003) Mycobacterium tuberculosis RecA intein, a LAGLIDADG homing endonuclease, displays $Mn^{2+}$ and DNA-dependent ATPase activity. In: Nucleic Acids Research, 31 (14). pp. 4184-4191.

Ganesh, N and Muniyappa, K (2003) Characterization of DNA Strand Transfer Promoted by Mycobacterium smegmatis RecA Reveals Functional Diversity with Mycobacterium tuberculosis RecA†. In: Biochemistry, 42 (23). pp. 7216-7225.

Ganesh, N and Muniyappa, K (2003) Mycobacterium smegmatis RecA Protein is Structurally Similar to but Functionally Distinct from Mycobacterium tuberculosis RecA. In: Proteins: Structure, Function, and Bioinformatics, 53 (1). pp. 6-17.

Guhan, N and Muniyappa, K (2003) Structural and functional characteristics of homing endonucleases. In: Critical Reviews in Biochemistry and Molecular Biology, 38 (3). pp. 199-248.

Datta, S and Ganesh, N and Chandra, Nagasuma R and Muniyappa, K and Vijayan, M (2003) Structural studies on MtRecA-nucleotide complexes: Insights into DNA and nucleotide binding and the structural signature of NTP recognition. In: Proteins: Structure, Function, and Genetics, 50 . pp. 474-485.

Guhan, N and Muniyappa, K (2002) The RecA intein of Mycobacterium tuberculosis promotes cleavage of ectopic DNA sites. Implications for the dispersal of inteins in natural populations. In: Journal of Biological Chemistry, 277 (43). pp. 40352-61.

Venkatesh, R and Ganesh, N and Guhan, N and Reddy, Sreedhar M and Chandrasekhar, T and Muniyappa, K (2002) RecX protein abrogates ATP hydrolysis and strand exchange promoted by RecA: Insights into negative regulation of homologous recombination. In: Proceedings of the National Academy of Sciences of the United States of America, 99 (19). pp. 12091-12096.

Guhan, N and Muniyappa, K (2002) Mycobacterium tuberculosis RecA Intein Possesses a Novel ATP-dependent Site-specific Double-stranded DNA Endonuclease Activity. In: The Journal of Biological Chemistry, 277 (18). pp. 16257-16264.

Reddy, Mothe Sreedhar and Guhan, N and Muniyappa, K (2001) Characterization of single-stranded DNA-binding proteins from Mycobacteria. The carboxyl-terminal of domain of SSB is essential for stable association with its cognate RecA protein. In: Journal of Biological Chemistry, 276 (49). pp. 45959-45968.

Bakshi, RP and Galande, S and Bali, P and Dighe, R and Muniyappa, K (2001) Developmental and hormonal regulation of type II DNA topoisomerase in rat testis. In: Journal of Molecular Endocrinology, 26 (3). pp. 193-206.

Bakshi, R and Galande, S and Muniyappa, K (2001) Substrate specificity plays an important role in uncoupling the catalytic and scaffolding activities of rat testis DNA topoisomerase IIalpha. In: Journal of Biomolecular Structure & Dynamics, 18 (5). pp. 749-760.

Bakshi, RP and Galande, S and Muniyappa, K (2001) Functional and regulatory characteristics of eukaryotic type II DNA topoisomerase. In: Critical Reviews in Biochemistry and Molecular Biology, 36 (1). pp. 1-37.

Reddy, Sreedhar M and Vaze, Moreshwar B and Madhusudan, K and Muniyappa, K (2000) Binding of SSB and RecA Protein to DNA-Containing Stem Loop Structures: SSB Ensures the Polarity of RecA Polymerization on Single-Stranded DNA. In: Biochemistry, 39 (46). pp. 14250-14262.

Muniyappa, K and Vaze, MB and Ganesh, N and Sreedhar Reddy, M and Guhan, N and Venkatesh, R (2000) Comparative genomics of Mycobacterium tuberculosis and Escherichia coli for recombination (rec) genes. In: Microbiology Comment, 146 (9). pp. 2093-2095.

Muniyappa, K and Anuradha, S and Byers, Breck (2000) Yeast meiosis-specific protein Hop1 binds to G4 DNA and promotes its formation. In: Molecular and Cellular Biology, 20 (4). pp. 1361-1369.

Datta, S and Prabu, MM and Vaze, MB and Ganesh, N and Chandra, Nagasuma R and Muniyappa, K and Vijayan, M (2000) Crystal Structures of Mycobacterium tuberculosis RecA and its complex ADP-AIF-4: implications for decreased ATPase activity and molecular aggregation. In: Nucleic Acids Research, 28 (24). pp. 4964-4973.

Vaze, Moreshwar B and Muniyappa, K (1999) RecA Protein of Mycobacterium tuberculosis Possesses pH-Dependent Homologous DNA Pairing and Strand Exchange Activities: Implications for Allele Exchange in Mycobacteria. In: Biochemistry, 38 (10). pp. 3175-3186.

Kironmai, Mary K and Muniyappa, K and Friedman, David B and Hollingsworth, Nancy M and Byers, Breck (1998) DNA-binding activities of HOP1 protein, a synaptonemal complex component from Saccharomyces cerevisiae. In: Molecular and Cellular Biology, 18 (3). pp. 1424-1435.

Ramdas, Jyoti and Muniyappa, K (1997) Recognition and alignment of homologous DNA sequences between minichromosomes and single-stranded DNA promoted by RecA protein. In: Molecular and General Genetics MGG, 249 (3). pp. 336-348.

Kironmai, Mary K and Muniyappa, K (1997) Alteration of telomeric sequences and senescence caused by mutations in RAD50 of Saccharomyces cerevisiae. In: Genes to Cells, 2 (7). pp. 443-455.

Galande, S and Muniyappa, K (1997) Effects of nucleosomes and anti-tumor drugs on the catalytic activity of type II DNA topoisomerase from rat testis. In: Biochemical Pharmacology, 53 (9). pp. 1229-1238.

Mythili, E and Kumar, Anand K and Muniyappa, K (1996) Characterization of the DNA-binding domain of beta protein, a component of phage lambda Red-pathway by UV catalyzed cross-linking. In: Gene, 182 (1-2). pp. 81-87.

Galande, Sanjeev and Muniyappa, K (1996) Purification and functional characterization of type II DNA topoisomerase from rat testis and comparison with topoisomerase II from liver. In: Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1308 (01). pp. 58-66.

Ajay Kumar, R and Vaze, Moreshwar B and Chandra, Nagasum and Vijayan, M and Muniyappa, K (1996) Functional characterization of the precursor and spliced forms of RecA protein of Mycobacterium tuberculosis. In: Biochemistry, 35 (6). 1793 -1802.

Kumar, KA and Mahalakshmi, S and Muniyappa, K (1993) DNA-induced conformational changes in RecA protein. Evidence for structural heterogeneity among nucleoprotein filaments and implications for homologous pairing. In: Journal of General Microbiology, 268 (35). pp. 26162-26170.

Muniyappa, K and Mythili, E (1993) Phage lambda beta protein, a component of general recombination, is associated with host ribosomal S1 protein. In: Biochemistry & Molecular Biology International, 31 (1). pp. 1-11.

Kumar, KA and Muniyappa, K (1992) Use of structure-directed DNA ligands to probe the binding of recA protein to narrow and wide grooves of DNA and on its ability to promote homologous pairing. In: Journal of Biological Chemistry, 267 (34). pp. 24824-24832.

Rould, Elizabeth and Muniyappa, K and Radding, Charles M (1992) Unwinding of heterologous DNA by RecA protein during the search for homologous sequences. In: Journal of Molecular Biology, 226 (1). pp. 127-139.

Muniyappa, K and Ramdas, J and Mythili, E and Galande, S (1991) Homologous pairing between nucleosome cores on a linear duplex DNA and nucleoprotein filaments of RecA protein-single stranded DNA. In: Biochimie, 73 (2-3). pp. 187-90.

Ramdas, Jyoti and Mythili, E and Muniyappa, K (1991) Nucleosomes on linear duplex DNA allow homologous pairing but prevent strand exchange promoted by RecA protein. In: PNAS, 88 (4). pp. 1344-1348.

Muniyappa, K and Williams, K and Chase, JW and Radding, CM (1990) Active nucleoprotein filaments of single-stranded binding protein and recA protein on single-stranded DNA have a regular repeating structure. In: Nucleic Acids Research, 18 (13). pp. 3967-3973.

Ramdas, Jyoti and Mythili, E and Muniyappa, K (1989) RecA Protein Promoted Homologous Pairing in Vitro. Pairing Between Linear Duplex DNA Bound to HU Protein (Nucleosome Cores) and Nucleoprotein Filaments of RecA Protein-Single-Stranded DNA. In: Journal of Biological Chemistry, 264 (29). pp. 17395-17400.

Flory, J and Tsang, SS and Muniyappa, K (1984) Isolation and visualization of active presynaptic filaments of recA protein and single-stranded DNA. In: Proc Natl Acad Sci Unit States Am, 81 (22). pp. 7026-30.

Muniyappa, K and Mendicino, J (1984) Binding and regulatory properties of phosphofructokinase from swine kidney. In: Molecular and Cellular Biochemistry, 63 (1). pp. 21-32.

Mascarenhas, C and Rajanna, B and Muniyappa, K and Desiraju, T (1984) Efficacy of a commercial rat feed & three other constituted diets in sustaining the body growth of rats. In: Indian Journal of Medical Education, 80 (AUG). pp. 218-227.

Muniyappa, K and Adiga, PR (1981) Nature of the thiamin-binding protein from chicken egg yolk. In: Biochemical Journal, 193 (3). 679-685..

Muniyappa, K and Adiga, Radhakantha P (1980) Purification and properties of riboflavin-binding protein from the egg white of the duck (Anas platyrhynckos). In: Biochimica et Biophysica Acta (BBA) - Protein Structure, 623 (2). pp. 339-347.

Muniyappa, K and Adiga, PR (1980) Isolation and characterization of riboflavin-binding protein from pregnant-rat serum. In: Biochemical Journal, 187 (2). pp. 537-540.

Muniyappa, K and Adiga, PR (1980) Occurrence and functional importance of a riboflavin-carrier protein in the pregnant rat. In: FEBS Letters, 110 (2). pp. 209-212.

Muniyappa, K and Adiga, PR (1979) Isolation and characterization of thiamin-binding protein from chicken egg white. In: Biochemical Journal, 177 (3). pp. 887-894.

Editorials/Short Communications

Adiga, PR and Muniyappa, K (1978) Estrogen induction and functional importance of carrier proteins for riboflavin and thiamine in the rat during gestation. In: Journal of Steroid Biochemistry and Molecular Biology, 9 (9). 829-829 .

This list was generated on Fri Mar 29 18:56:46 2024 IST.