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Boshoff, Helena Ingrid and Tripathi, Ashutosh and Anand, Kushi and Das, Mayashree and O’Niel, Ruchika Annie and PS, Sabarinath and Thakur, Chandrani and RL, Raghunatha Reddy and Rajmani, Raju S and Chandra, Nagasuma and Laxman, Sunil and Singh, Amit (2022) Mycobacterium tuberculosis requires SufT for Fe-S cluster maturation, metabolism, and survival in vivo. In: PLOS Pathogens, 18 (4). ISSN 1553-7374
Nagarajan, Deepesh and Roy, Natasha and Kulkarni, Omkar and Nanajkar, Neha and Datey, Akshay and Ravichandran, Sathyabaarathi and Thakur, Chandrani and Sandeep, T and Aprameya, Indumathi and Sarma, Siddhartha P and Chakravortty, Dipshikha and Chandra, Nagasuma (2019) Omega 76: A designed antimicrobial peptide to combat carbapenem- and tigecycline-resistant Acinetobacter baumannii. In: SCIENCE ADVANCES, 5 (7).
Chandra, Nagasuma (2019) Identifying and targeting the Achilles heel of drug resistant bacteria. In: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 37 (1, SI). pp. 15-16.
Nagarajan, Deepesh and Sukumaran, Sujeesh and Deka, Geeta and Krishnamurthy, Kiran and Atreya, Hanudatta S and Chandra, Nagasuma (2018) Design of a heme-binding peptide motif adopting a beta-hairpin conformation. In: JOURNAL OF BIOLOGICAL CHEMISTRY, 293 (24). pp. 9412-9422.
Bhagavat, Raghu and Sankar, Santhosh and Srinivasan, Narayanaswamy and Chandra, Nagasuma (2018) An Augmented Pocketome: Detection and Analysis of Small-Molecule Binding Pockets in Proteins of Known 3D Structure. In: STRUCTURE, 26 (3). 499+.
Nagarajan, Deepesh and Nagarajan, Tushar and Roy, Natasha and Kulkarni, Omkar and Ravichandran, Sathyabaarathi and Mishra, Madhulika and Chakravortty, Madhulika and Chandra, Nagasuma (2018) Computational antimicrobial peptide design and evaluation against multidrug-resistant clinical isolates of bacteria. In: JOURNAL OF BIOLOGICAL CHEMISTRY, 293 (10). pp. 3492-3509.
Sambaturu, Narmada and Mukherjee, Sumanta and Lopez-Garcia, Martin and Molina-Paris, Carmen and Menonm, Gautam I and Chandra, Nagasuma (2018) Role of genetic heterogeneity in determining the epidemiological severity of H1 N1 influenza. In: PLOS COMPUTATIONAL BIOLOGY, 14 (3).
Gopalan, Akilandeswari and Bhagavat, Raghu and Chandra, Nagasuma and Subbarao, Savithri Handanahal and Raja, Alamelu and Bethunaickan, Ramalingam (2018) Biophysical and biochemical characterization of Rv3405c, a tetracycline repressor protein from Mycobacterium tuberculosis. In: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 496 (3). pp. 799-805.
Bhaskarla, Chetana and Bhosale, Manoj and Banerjee, Pip and Chandra, Nagasuma and Nandi, Dipankar (2018) Protein Tagging, Destruction and Infection. In: CURRENT PROTEIN & PEPTIDE SCIENCE, 19 (2). pp. 155-171.
Sambarey, Awanti and Devaprasad, Abhinandan and Baloni, Priyanka and Mishra, Madhulika and Mohan, Abhilash and Tyagi, Priyanka and Singh, Amit and Akshata, JS and Sultana, Razia and Buggi, Shashidhar and Chandra, Nagasuma (2017) Meta-analysis of host response networks identifies a common core in tuberculosis. In: npj Systems Biology and Applications, 3 (1). ISSN 2056-7189
Blagavat, Raghu and Srinivasan, Narayanaswamy and Chandra, Nagasuma (2017) Deciphering common recognition principles of nucleoside mono/di and tri-phosphates binding in diverse proteins via structural matching of their binding sites. In: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 85 (9). pp. 1699-1712.
Mishra, Saurabh and Shukla, Prashant and Bhaskar, Ashima and Anand, Kushi and Baloni, Priyanka and Jha, Rajiv Kumar and Mohan, Abhilash and Rajmani, Raju S and Nagaraja, Valakunja and Chandra, Nagasuma and Singh, Amit (2017) Efficacy of beta-lactam/beta-lactamase inhibitor combination is linked to WhiB4-mediated changes in redox physiology of Mycobacterium tuberculosis. In: ELIFE, 6 .
Ramakrishnan, Gayatri and Chandra, Nagasuma and Srinivasan, Narayanaswamy (2017) Exploring anti-malarial potential of FDA approved drugs: an in silico approach. In: MALARIA JOURNAL, 16 .
Metri, Rahul and Mohan, Abhilash and Nsengimana, Jeremie and Pozniak, Joanna and Molina-Paris, Carmen and Newton-Bishop, Julia and Bishop, David and Chandra, Nagasuma (2017) Identification of a gene signature for discriminating metastatic from primary melanoma using a molecular interaction network approach. In: SCIENTIFIC REPORTS, 7 .
Metri, Rahul and Mohan, Abhilash and Nsengimana, Jeremie and Pozniak, Joanna and Molina-Paris, Carmen and Newton-Bishop, Julia and Bishop, David and Chandra, Nagasuma (2017) Identification of a gene signature for discriminating metastatic from primary melanoma using a molecular interaction network approach. In: SCIENTIFIC REPORTS, 7 .
Sahu, Umakant and Rajendra, Vinod K H and Kapnoor, Shankar S and Bhagavat, Raghu and Chandra, Nagasuma and Rangarajan, Pundi N (2017) Methionine synthase is localized to the nucleus in Pichia pastoris and Candida albicans and to the cytoplasm in Saccharomyces cerevisiae. In: JOURNAL OF BIOLOGICAL CHEMISTRY, 292 (36). pp. 14730-14746.
Metri, Rahul and Saxena, Shikhar and Mishra, Madhulika and Chandra, Nagasuma (2017) Modelling metabolic rewiring during melanoma progression using Flux Balance Analysis. In: IEEE International Conference on Bioinformatics and Biomedicine (IEEE BIBM), NOV 13-16, 2017, Kansas City, MI, pp. 134-137.
Mudgal, Richa and Srinivasan, Narayanaswamy and Chandra, Nagasuma (2017) Resolving protein structure-function-binding site relationships from a binding site similarity network perspective. In: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 85 (7). pp. 1319-1335.
Korla, Kalyani and Chandra, Nagasuma (2017) A Systems Perspective of Signalling Networks in Host-Pathogen Interactions. In: JOURNAL OF THE INDIAN INSTITUTE OF SCIENCE, 97 (1). pp. 41-57.
Ramakrishnan, Gayatri and Jain, Abha and Chandra, Nagasuma and Srinivasan, Narayanaswamy (2016) Computational recognition and analysis of hitherto uncharacterized nucleotide cyclase-like proteins in bacteria. In: BIOLOGY DIRECT, 11 .
Marathe, Sandhya Amol and Balakrishnan, Arjun and Negi, Vidya Devi and Sakorey, Deepika and Chandra, Nagasuma and Chakravortty, Dipshikha (2016) Curcumin Reduces the Motility of Salmonella enterica Serovar Typhimurium by Binding to the Flagella, Thereby Leading to Flagellar Fragility and Shedding. In: JOURNAL OF BACTERIOLOGY, 198 (13). pp. 1798-1811.
Karyala, Prashanthi and Metri, Rahul and Bathula, Christopher and Yelamanchi, Syam K and Sahoo, Lipika and Arjunan, Selvam and Sastri, Narayan P and Chandra, Nagasuma (2016) DenHunt - A Comprehensive Database of the Intricate Network of Dengue-Human Interactions. In: PLOS NEGLECTED TROPICAL DISEASES, 10 (9).
Gilbert, Harry J. and Chandra, Nagasuma (2016) Editorial overview: Carbohydrate-protein interactions and glycosylation: integrating structural biology, informatics and systems modelling to understand glycan structure and glycan-protein interactions. In: CURRENT OPINION IN STRUCTURAL BIOLOGY, 40 . V-VIII.
Sambaturu, Narmada and Mishra, Madhulika and Chandra, Nagasuma (2016) EpiTracer - an algorithm for identifying epicenters in condition-specific biological networks. In: BMC GENOMICS, 17 (4).
Mukherjee, Sumanta and Bhattacharyya, Chiranjib and Chandra, Nagasuma (2016) HLaffy: estimating peptide affinities for Class-1 HLA molecules by learning position-specific pair potentials. In: BIOINFORMATICS, 32 (15). pp. 2297-2305.
Chandrashekara, S and Anupama, KR and Sambarey, Awanti and Chandra, Nagasuma (2016) High IL-6 and low IL-15 levels mark the presence of TB infection: A preliminary study. In: CYTOKINE, 81 . pp. 57-62.
Padiadpu, Jyothi and Baloni, Priyanka and Anand, Kushi and Munshi, MohamedHusen and Thakur, Chandrani and Mohan, Abhilash and Singh, Amit and Chandra, Nagasuma (2016) Identifying and Tackling Emergent Vulnerability in Drug-Resistant Mycobacteria. In: ACS INFECTIOUS DISEASES, 2 (9). pp. 592-607.
Shivashankar, Nithin and Patil, Sonali and Bhosle, Amrisha and Chandra, Nagasuma and Natarajan, Vijay (2016) MS3ALIGN: an efficient molecular surface aligner using the topology of surface curvature. In: BMC BIOINFORMATICS, 17 .
Bhosle, Amrisha and Chandra, Nagasuma (2016) Structural analysis of dihydrofolate reductases enables rationalization of antifolate binding affinities and suggests repurposing possibilities. In: FEBS JOURNAL, 283 (6). pp. 1139-1167.
Singh, Amandeep and Bhagavat, Raghu and Vijayan, M and Chandra, Nagasuma (2016) A comparative analysis of the DNA recombination repair pathway in mycobacterial genomes. In: TUBERCULOSIS, 99 . pp. 109-119.
Baloni, Priyanka and Chandra, Nagasuma (2015) Architectural plan of transcriptional regulation in Mycobacterium tuberculosis. In: TRENDS IN MICROBIOLOGY, 23 (3). pp. 123-125.
Bin Masood, Talha and Sandhya, Sankaran and Chandra, Nagasuma and Natarajan, Vijay (2015) CHEXVIS: a tool for molecular channel extraction and visualization. In: BMC BIOINFORMATICS, 16 .
Mudgal, Richa and Sandhya, Sankaran and Chandra, Nagasuma and Srinivasan, Narayanaswamy (2015) De-DUFing the DUFs: Deciphering distant evolutionary relationships of Domains of Unknown Function using sensitive homology detection methods. In: BIOLOGY DIRECT, 10 .
Mukherjee, Sumanta and Warwicker, Jim and Chandra, Nagasuma (2015) Deciphering complex patterns of class-I HLA-peptide cross-reactivity via hierarchical grouping. In: IMMUNOLOGY AND CELL BIOLOGY, 93 (6). pp. 522-532.
Dighe, Anasuya and Chandra, Nagasuma and Vishveshwara, Saraswathi and Ananthasuresh, GK (2015) Dissecting Ligand Binding Sites : A Layer at a Time. In: BIOPHYSICAL JOURNAL, 108 (2, 1). 216A.
Sambaturu, Narmada and Mishra, Madhulika and Chandra, Nagasuma (2015) EpiTracer - an algorithm for identifying epicenters in condition-specific biological networks. In: IEEE International Conference on Bioinformatics and Biomedicine, NOV 09-12, 2015, Washington, DC, pp. 177-182.
Ghosh, Soma and Chandra, Nagasuma and Vishveshwara, Saraswathi (2015) Influence of iron on iron dependent repressor (IdeR) activation and DNA binding. In: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 33 (1). p. 8.
Ghosh, Soma and Chandra, Nagasuma and Vishveshwara, Saraswathi (2015) Investigating the Mechanism of Iron Dependent Repressor (IDER) Activation and DNA Binding. In: BIOPHYSICAL JOURNAL, 108 (2, 1). 377A.
Sharadamma, Narayanaswamy and Harshavardhana, Yadumurthy and Ravishankar, Apoorva and Anand, Praveen and Chandra, Nagasuma and Muniyappa, K (2015) Molecular Dissection of Mycobacterium tuberculosis Integration Host Factor Reveals Novel Insights into the Mode of DNA Binding and Nucleoid Compaction. In: BIOCHEMISTRY, 54 (26). pp. 4142-4160.
Anand, Praveen and Chandra, Nagasuma (2014) Characterizing the pocketome of Mycobacterium tuberculosis and application in rationalizing polypharmacological target selection. In: SCIENTIFIC REPORTS, 4 .
Bhagavat, Raghu and Chandra, Nagasuma (2014) Common recognition principles across diverse sequence and structural families of sialic acid binding proteins. In: GLYCOBIOLOGY, 24 (1). pp. 5-16.
Mudgal, Richa and Sowdhamini, Ramanathan and Chandra, Nagasuma and Srinivasan, Narayanaswamy and Sandhya, Sankaran (2014) Filling-in Void and Sparse Regions in Protein Sequence Space by Protein-Like Artificial Sequences Enables Remarkable Enhancement in Remote Homology Detection Capability. In: JOURNAL OF MOLECULAR BIOLOGY, 426 (4). pp. 962-979.
Pentakota, Satya Krishna and Sandhya, Sankaran and Sikarwar, Arun P and Chandra, Nagasuma and Rao, Manchanahalli Satyanarayana R (2014) Mapping Post-translational Modifications of Mammalian Testicular Specific Histone Variant TH2B in Tetraploid and Haploid Germ Cells and Their Implications on the Dynamics of Nucleosome Structure. In: JOURNAL OF PROTEOME RESEARCH, 13 (12). pp. 5603-5617.
Sharadamma, Narayanaswamy and Harshavardhana, Yadumurthy and Ravishankar, Apoorva and Anand, Praveen and Chandra, Nagasuma and Muniyappa, K (2014) Molecular Dissection of Mycobacterium tuberculosis Integration Host Factor Reveals Novel Insights into the Mode of DNA Binding and Nucleoid Compaction. In: JOURNAL OF BIOLOGICAL CHEMISTRY, 289 (49). pp. 34325-34340.
Anand, Praveen and Nagarajan, Deepesh and Mukherjee, Sumanta and Chandra, Nagasuma (2014) PLIC: protein-ligand interaction clusters. In: DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION .
Mukherjee, Sumanta and Chandra, Nagasuma (2013) Computational framework to integrate the effect of antigen recognition on disease epidemiology outcome: multi-scale approach. In: 4th Annual ORNL Biomedical Sciences and Engineering Conference on Collaborative Biomedical Innovations, MAY 21-23, 2013, Biomed Sci & Engn Ctr, Oak Ridge Natl Lab, Oak Ridge, TN Date: MAY 21-23, 2013 .
Mukherjee, Sumanta and Sambarey, Awanti and Prashanthi, Karyala and Chandra, Nagasuma (2013) Current trends in modeling hostpathogen interactions. In: WILEY INTERDISCIPLINARY REVIEWS-DATA MINING AND KNOWLEDGE DISCOVERY, 3 (2). pp. 109-128.
Mukherjee, Sumanta and Sambarey, Awanti and Prashanthi, Karyala and Chandra, Nagasuma (2013) Current trends in modeling hostpathogen interactions. In: WILEY INTERDISCIPLINARY REVIEWS-DATA MINING AND KNOWLEDGE DISCOVERY, 3 (2). pp. 109-128.
Ghosh, Soma and Vishveshwara, Saraswathi and Chandra, Nagasuma (2013) Inferring biochemical routes from biochemical networks. In: 4th Annual ORNL Biomedical Sciences and Engineering Conference on Collaborative Biomedical Innovations, MAY 21-23, 2013, Biomed Sci & Engn Ctr, Oak Ridge Natl Lab, Oak Ridge, TN.
Sambarey, Awanti and Prashanthi, Karyala and Chandra, Nagasuma (2013) Mining large-scale response networks reveals `topmost activities' in Mycobacterium tuberculosis infection. In: SCIENTIFIC REPORTS, 3 .
Nagarajan, Deepesh and Chandra, Nagasuma (2013) PocketMatch (version 2.0): A parallel algorithm for the detection of structural similarities between protein ligand binding-sites. In: National Conference on Parallel Computing Technologies (PARCOMPTECH), FEB 21-23, 2013, Bangalore, INDIA.
Ghosh, Soma and Baloni, Priyanka and Mukherjee, Sumanta and Anand, Praveen and Chandra, Nagasuma (2013) A multi-level multi-scale approach to study essential genes in Mycobacterium tuberculosis. In: BMC SYSTEMS BIOLOGY, 7 .
Vashisht, Rohit and Mondal, Anupam Kumar and Jain, Akanksha and Shah, Anup and Vishnoi, Priti and Priyadarshini, Priyanka and Bhattacharyya, Kausik and Rohira, Harsha and Bhat, Ashwini G and Passi, Anurag and Mukherjee, Keya and Choudhary, Kumari Sonal and Kumar, Vikas and Arora, Anshula and Munusamy, Prabhakaran and Subramanian, Ahalyaa and Venkatachalam, Aparna and Gayathri, S and Raj, Sweety and Chitra, Vijaya and Verma, Kaveri and Zaheer, Salman and Balaganesh, J and Gurusamy, Malarvizhi and Razeeth, Mohammed and Raja, Ilamathi and Thandapani, Madhumohan and Mevada, Vishal and Soni, Raviraj and Rana, Shruti and Ramanna, Girish Muthagadhalli and Raghavan, Swetha and Subramanya, Sunil N and Kholia, Trupti and Patel, Rajesh and Bhavnani, Varsha and Chiranjeevi, Lakavath and Sengupta, Soumi and Singh, Pankaj Kumar and Atray, Naresh and Gandhi, Swati and Avasthi, Tiruvayipati Suma and Nisthar, Shefin and Anurag, Meenakshi and Sharma, Pratibha and Hasija, Yasha and Dash, Debasis and Sharma, Arun and Scaria, Vinod and Thomas, Zakir and Chandra, Nagasuma and Brahmachari, Samir K and Bhardwaj, Anshu and Consortium, OSDD (2012) Crowd Sourcing a New Paradigm for Interactome Driven Drug Target Identification in Mycobacterium tuberculosis. In: PLOS ONE, 7 (7).
Anand, Praveen and Yeturu, Kalidas and Chandra, Nagasuma (2012) PocketAnnotate: towards site-based function annotation. In: NUCLEIC ACIDS RESEARCH, 40 (W1). W400-W408.
Mishra, Saurabh and Bhagavat, Raghu and Chandra, Nagasuma and Vijayarangan, Namperumalsamy and Rajeswari, Haryadi and Ajitkumar, Parthasarathi (2012) Cloning, expression, purification, and biochemical characterisation of the FIC motif containing protein of Mycobacterium tuberculosis. In: PROTEIN EXPRESSION AND PURIFICATION, 86 (1). pp. 58-67.
Chandra, Nagasuma and Padiadpu, Jyothi (2012) Network approaches to drug discovery. In: EXPERT OPINION ON DRUG DISCOVERY, 8 (1). pp. 7-20.
Bhardwaj, Anshu and Scaria, Vinod and Raghava, Gajendra Pal Singh and Lynn, Andrew Michael and Chandra, Nagasuma and Banerjee, Sulagna and Raghunandanan, Muthukurussi V and Pandey, Vikas and Taneja, Bhupesh and Yadav, Jyoti and Dash, Debasis and Bhattacharya, Jaijit and Misra, Amit and Kumar, Anil and Ramachandran, Srinivasan and Thomas, Zakir and Brahmachari, Samir K (2011) Open source drug discovery- A new paradigm of collaborative research in tuberculosis drug development. In: Tuberculosis, 91 (5, SI). pp. 479-486.
Chandra, Nagasuma (2009) Computational systems approach for drug target discovery. In: Expert Opinion on Drug Discovery, 4 (12). pp. 1221-1236.
