Towards the development of a table-top system for tumour delineation using electro-thermal characterization

Vishnu, AGK and De, T and Ariun, BS and Rangarajan, A and Pandya, HJ (2021) Towards the development of a table-top system for tumour delineation using electro-thermal characterization. In: 7th IEEE International Conference on Electronics, Computing and Communication Technologies, 9-11 Jul 2021, Bangalore.

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Abstract

We propose a table-top setup integrated with MEMS-based sensors for the electro-thermal characterization of tumour and normal tissues. The bulk DC conductivity (as a function of temperature) and normalized conductance (as a function of excitation frequency) is quantified to delineate between freshly excised tumour from murine xenograft tumour model and normal murine tissues. It is observed that the tumour tissues have a higher DC and AC conductivity compared to normal tissues from the lung and liver. The DC conductivity of the tumour tissue drops more drastically as a function of temperature compared to the normal tissue. Likewise, the AC conductivity of tumour tissue also increases more rapidly beyond a cutoff frequency. These observations suggest that such an electro-thermal characterization of excised tissues could serve as a basis for tumour delineation. © 2021 IEEE.

Item Type:	Conference Paper
Publication:	Proceedings of CONECCT 2021: 7th IEEE International Conference on Electronics, Computing and Communication Technologies
Publisher:	Institute of Electrical and Electronics Engineers Inc.
Additional Information:	The copyright for this article belongs to Institute of Electrical and Electronics Engineers Inc.
Keywords:	Cutoff frequency; Mechanics; MEMS; Tumors, A.C conductivity; Biomedical systems; Electrical conductivity; Impedance spectroscopy; Normal tissue; Table top system; Table-top; Thermal characterization; Tumor delineation; Tumour tissue, Histology
Department/Centre:	Division of Interdisciplinary Sciences > Centre for Biosystems Science and Engineering
Date Deposited:	07 Feb 2022 12:21
Last Modified:	07 Feb 2022 12:21
URI:	http://eprints.iisc.ac.in/id/eprint/71282

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