Investigating the dynamics of the magnetic micromotors in human blood

Venugopalan, PL and Ghosh, A (2021) Investigating the dynamics of the magnetic micromotors in human blood. In: Langmuir, 37 (01). pp. 289-296.

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Abstract

The field of micromotors has been growing exponentially with increased emphasis on biomedical applications, with various in vivo demonstrations of targeted drug delivery, biosensing, and gene delivery, among others. In parallel, these micromotors have been recently used for probing the rheological properties of both intra- and extracellular environments. Here, we demonstrate the application of magnetic micromotors for investigation of rheological properties of human blood. While there are several techniques to sense mechanical properties of blood, such as deformability of the red blood cells, this is the first experimental observation of using micromotors for these biophysical investigations. We hope that this will lead to a better understanding of the nature of interactions of micromotors with biological systems and expand the scope of micromotors for probing other related systems, such as interstitial fluids and other complex biological fluids. © XXXX American Chemical Society.

Item Type:	Journal Article
Publication:	Langmuir
Publisher:	American Chemical Society
Additional Information:	The copyright for this belongs to American Chemical Society.
Keywords:	Controlled drug delivery; Gene transfer; Medical applications; Micromotors; Rheology; Targeted drug delivery, Biological fluids; Biomedical applications; Extracellular environments; Interstitial fluids; Magnetic micromotors; Red blood cell; Related systems; Rheological property, Blood
Department/Centre:	Division of Interdisciplinary Sciences > Centre for Nano Science and Engineering Division of Physical & Mathematical Sciences > Physics
Date Deposited:	24 Dec 2021 10:25
Last Modified:	24 Dec 2021 10:25
URI:	http://eprints.iisc.ac.in/id/eprint/67805

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