Pahal, S and Badnikar, K and Ghate, V and Bhutani, U and Nayak, MM and Subramanyam, DN and Vemula, PK (2021) Microneedles for Extended Transdermal Therapeutics: A Route to Advanced Healthcare. In: European Journal of Pharmaceutics and Biopharmaceutics, 159 . pp. 151-169.
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Abstract
Sustained release of drugs over a pre-determined period is required to maintain an effective therapeutic dose for variety of drug delivery applications. Transdermal devices such as polymeric microneedle patches and other microneedle-based devices have been utilized for sustained release of their payload. Swift clearing of drugs can be prevented either by designing a slow-degrading polymeric matrix or by providing physiochemical triggers to different microneedle-based devices for on-demand release. These long-acting transdermal devices prevent the burst release of drugs. This review highlights the recent advances of microneedle-based devices for sustained release of vaccines, hormones, and antiretrovirals with their prospective safe clinical translation. © 2020 Elsevier B.V.
Item Type: | Journal Article |
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Publication: | European Journal of Pharmaceutics and Biopharmaceutics |
Publisher: | Elsevier B.V. |
Additional Information: | The copyright for this article belongs to Elsevier B.V. |
Department/Centre: | Division of Electrical Sciences > Electronic Systems Engineering (Formerly Centre for Electronic Design & Technology) Division of Interdisciplinary Sciences > Centre for Nano Science and Engineering |
Date Deposited: | 31 Dec 2021 06:07 |
Last Modified: | 31 Dec 2021 06:07 |
URI: | http://eprints.iisc.ac.in/id/eprint/67796 |
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