Manna, S and Someswara Ashwathappa, PK and Prabhu, KR (2020) Visible light-mediated: Ipso -annulation of activated alkynes: Access to 3-alkylated spiro4,5-trienones, thiaspiro4,5-trienones and azaspiro4,5-trienones. In: Chemical Communications, 56 (86). pp. 13165-13168.
PDF
che_com_56-86_13165-13168_2020.pdf - Published Version Restricted to Registered users only Download (2MB) | Request a copy |
|
PDF
d0cc01217c1.pdf - Published Supplemental Material Restricted to Registered users only Download (6MB) | Request a copy |
Abstract
A novel method for chemoselective difunctionalization of activated alkynes for synthesizing 3-alkylated spiro4,5-trienones, thiaspiro4,5-trienones and spirolactams has been uncovered using photoredox catalysis under visible light conditions. The rarely used tricarbonyl compounds in photoredox catalysis were used as the alkylating source. A remarkable functional group tolerance was observed, and the application of the method has been showcased by transforming tricarbonylated spirolactams to their corresponding monocarbonylated products, which are difficult to access using traditional methods. This journal is © The Royal Society of Chemistry.
Item Type: | Journal Article |
---|---|
Publication: | Chemical Communications |
Publisher: | Royal Society of Chemistry |
Additional Information: | The copyright of this article belongs to Royal Society of Chemistry |
Keywords: | Catalysis; Hydrocarbons, Activated alkynes; Chemoselective; Difunctionalization; Photoredox catalysis; Visible light, Light |
Department/Centre: | Division of Chemical Sciences > Organic Chemistry |
Date Deposited: | 27 Jan 2021 06:31 |
Last Modified: | 27 Jan 2021 06:31 |
URI: | http://eprints.iisc.ac.in/id/eprint/67314 |
Actions (login required)
View Item |