Sticking and Signalling at the Synapse: Two Sides of the Same Coin?

Babu, K (2020) Sticking and Signalling at the Synapse: Two Sides of the Same Coin? In: Resonance, 25 (3). pp. 419-429.

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Abstract

Our brain and nervous system coordinate all activities of our body and its interaction with the environment. Our brain is made up of a large number of cells called neurons that form specialised points of contacts with other neurons. These contacts are called synapses. The development and functioning of these synapses are clearly vital for nervous system function. A set of molecules call Cell AdhesionMolecules (CAMs) have been shown to be required for the development and maintenance of synapses. More recent work with CAMs indicates that these molecules are also required for signalling and hence normal functioning of synapses. Here, I discuss how CAMs function both in normal synapse development and in signalling at the synapse. © 2020, Indian Academy of Sciences.

Item Type:	Journal Article
Publication:	Resonance
Publisher:	Springer
Additional Information:	copy right for this article belongs to Springer
Keywords:	Synapse, cell adhesion molecules (CAMs), signalling, C. elegans
Department/Centre:	Division of Biological Sciences > Centre for Neuroscience
Date Deposited:	19 Oct 2020 09:34
Last Modified:	19 Oct 2020 09:34
URI:	http://eprints.iisc.ac.in/id/eprint/65297

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