Sarkar, Rahul and Mukherjee, Santanu (2019) Enantioselective Direct Vinylogous Allylic Alkylation of 4-Methylquinolones under Iridium Catalysis. In: ORGANIC LETTERS, 21 (13). pp. 5315-5320.
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Official URL: https://dx.doi.org/10.1021/acs.orglett.9b01934
Abstract
The first enantioselective vinylogous allylic alkylation of 4-methylquinolones has been developed. This iridium-catalyzed reaction introduces an allyl group at the gamma-position of 4-methyl-2-quinolones with exclusive branched selectivity and an excellent level of enantioselectivity. This in turn allows for the enantioselective synthesis of gamma-allylquinolines and related nitrogenous heterocycles. This is the first application of 4-methylquinolones in an enantioselective transformation.
| Item Type: | Journal Article |
|---|---|
| Publication: | ORGANIC LETTERS |
| Publisher: | AMER CHEMICAL SOC |
| Additional Information: | copyright for this article belongs to AMER CHEMICAL SOC |
| Department/Centre: | Division of Chemical Sciences > Organic Chemistry |
| Date Deposited: | 22 Aug 2019 10:35 |
| Last Modified: | 22 Aug 2019 10:35 |
| URI: | http://eprints.iisc.ac.in/id/eprint/63305 |
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