MULTI-MODAL IMPEDANCE SPECTROSCOPY DEVICE FOR SIMULTANEOUS MEASUREMENT OF ELECTRICAL AND MECHANICAL PROPERTIES OF CELLS

Mahesh, Karthik and Parate, Kshama and Shah, Charan M and Varma, Manoj M and Sen, Prosenjit (2017) MULTI-MODAL IMPEDANCE SPECTROSCOPY DEVICE FOR SIMULTANEOUS MEASUREMENT OF ELECTRICAL AND MECHANICAL PROPERTIES OF CELLS. In: 30th IEEE International Conference on Micro Electro Mechanical Systems (MEMS), JAN 22-26, 2017, Las Vegas, NV, pp. 1256-1259.

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Abstract

We demonstrate a novel microfluidic device based on electrical impedance spectroscopy (EIS) which independently measures the electrical properties of cells and simultaneously estimates their mechanical properties by measuring transit times across a mechanical constriction. The device also allows electrically probing the effect of mechanical squeezing on the cell. Compared to conventional EIS techniques that measures the electrical impedance of cells solely across a constriction, the proposed technique offers more versatility and enables multi-modal analysis of cellular properties.

Item Type:	Conference Proceedings
Series.:	Proceedings IEEE Micro Electro Mechanical Systems
Publisher:	IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA
Additional Information:	30th IEEE International Conference on Micro Electro Mechanical Systems (MEMS), Las Vegas, NV, JAN 22-26, 2017
Department/Centre:	Division of Interdisciplinary Sciences > Centre for Nano Science and Engineering
Date Deposited:	28 Jun 2017 06:27
Last Modified:	28 Jun 2017 06:27
URI:	http://eprints.iisc.ac.in/id/eprint/57299

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