A molecular beacon-based DNA switch for reversible pH sensing in vesicles and live cells

Narayanaswamy, Nagarjun and Nair, Raji R and Suseela, YV and Saini, Deepak Kumar and Govindaraju, T (2016) A molecular beacon-based DNA switch for reversible pH sensing in vesicles and live cells. In: CHEMICAL COMMUNICATIONS, 52 (56). pp. 8741-8744.

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Abstract

In this Communication, a molecular beacon-based DNA switch (LMB) is developed as an efficient and reversible pH sensing probe. Remarkably, LMB exhibited reversible structural transition between the closed (molecular beacon) and open (A-motif) states very efficiently in synthetic vesicles and live cells without the need for any transfection agents.

Item Type:	Journal Article
Publication:	CHEMICAL COMMUNICATIONS
Publisher:	ROYAL SOC CHEMISTRY
Additional Information:	Copy right for this article belongs to the ROYAL SOC CHEMISTRY, THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND
Department/Centre:	Division of Biological Sciences > Molecular Reproduction, Development & Genetics
Date Deposited:	22 Aug 2016 09:48
Last Modified:	22 Aug 2016 09:48
URI:	http://eprints.iisc.ac.in/id/eprint/54501

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