Non-enzymatic electronic detection of glucose using aminophenylboronic acid functionalized reduced graphene oxide

Vasu, KS and Sridevi, S and Sampath, S and Sood, AK (2015) Non-enzymatic electronic detection of glucose using aminophenylboronic acid functionalized reduced graphene oxide. In: SENSORS AND ACTUATORS B-CHEMICAL, 221 . pp. 1209-1214.

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Abstract

We report the non-enzymatic electronic detection of glucose using field effect transistor (FET) devices made of aminophenylboronic acid (APBA) functionalized reduced graphene oxide (RGO). Detection of glucose molecules was carried out over a wide dynamic range of concentration varying from 100 pM to 100 mM with a detection limit of similar to 2 nM using both covalently and non-covalently functionalized APBA-RGO complex. The normalized change in electrical conductance data shows that the FET devices made of non-covalently functionalized APBA-RGO complex (nc-APBA-RGO) exhibited a linear response to glucose aqueous solution of concentrations varying from 1 nM to 10 mM and showed 4 times enhanced sensitivity over the devices made of covalently functionalized APBA-RGO complex (c-APBA-RGO). Specificity of APBA-RGO complex to glucose is confirmed from the observation of negligible change in electrical conductance after exposure to 0.1 mM of lactose and other interfering factors. (C) 2015 Elsevier B.V. All rights reserved.

Item Type:	Journal Article
Publication:	SENSORS AND ACTUATORS B-CHEMICAL
Publisher:	ELSEVIER SCIENCE SA
Additional Information:	Copy right for this article belongs to the ELSEVIER SCIENCE SA, PO BOX 564, 1001 LAUSANNE, SWITZERLAND
Keywords:	Glucose; Aminophenylboronic acid; Graphene oxide; Field effect transistor; Non-enzymatic detection
Department/Centre:	Division of Chemical Sciences > Inorganic & Physical Chemistry Division of Physical & Mathematical Sciences > Instrumentation Appiled Physics Division of Physical & Mathematical Sciences > Physics
Date Deposited:	12 Nov 2015 05:14
Last Modified:	12 Nov 2015 05:14
URI:	http://eprints.iisc.ac.in/id/eprint/52745

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