Fast and accurate quantification using Genetic Algorithm optimized H-1-C-13 refocused constant-time INEPT

Manu, VS and Kumar, Anil (2013) Fast and accurate quantification using Genetic Algorithm optimized H-1-C-13 refocused constant-time INEPT. In: JOURNAL OF MAGNETIC RESONANCE, 234 . pp. 106-111.

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Abstract

Using Genetic Algorithm, a global optimization method inspired by nature's evolutionary process, we have improved the quantitative refocused constant-time INEPT experiment (Q-INEPT-CT) of Makela et al. (JMR 204 (2010) 124-130) with various optimization constraints. The improved `average polarization transfer' and `min-max difference' of new delay sets effectively reduces the experimental time by a factor of two (compared with Q-INEPT-CT, Makela et al.) without compromising on accuracy. We also discuss a quantitative spectral editing technique based on average polarization transfer. (C) 2013 Elsevier Inc. All rights reserved.

Item Type:	Journal Article
Publication:	JOURNAL OF MAGNETIC RESONANCE
Publisher:	ACADEMIC PRESS INC ELSEVIER SCIENCE
Additional Information:	Copyright of this article is belongs to ACADEMIC PRESS INC ELSEVIER SCIENCE
Keywords:	Genetic Algorithm; Refocused-INEPT; Quantification; Spectral simplification
Department/Centre:	Division of Chemical Sciences > NMR Research Centre (Formerly Sophisticated Instruments Facility) Division of Physical & Mathematical Sciences > Physics
Date Deposited:	30 Sep 2013 04:54
Last Modified:	30 Sep 2013 04:54
URI:	http://eprints.iisc.ac.in/id/eprint/47341

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