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Chicken prealbumin: Nature of its heterogeneity and binding of plasma retinol-binding protein and thyroid hormones

Bhat, Krishna K and Cama, HR (1978) Chicken prealbumin: Nature of its heterogeneity and binding of plasma retinol-binding protein and thyroid hormones. In: Proceedings of the Indian Academy of Sciences Section -B, 87 (7). pp. 195-203.

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Abstract

The heterogeneity of chicken prealbumin (PA) has been shown to be due to the occurrence of three different plasma proteins (PA1 PA2 and PA3). Equilibrium dialysis studies revealed that the thyroid hormones bind specifically to PA2. These hormones bind at the same site on PA2. Circular dichroism studies failed to reveal conformational changes on interaction of retinol-binding protein and thyroid hormone with PA2. Both retinol-binding protein and thyroid hormone are independently transported by PA2.

Item Type: Journal Article
Publication: Proceedings of the Indian Academy of Sciences Section -B
Publisher: Indian Academy of Sciences
Additional Information: Copyright of this article belongs to Indian Academy of Sciences.
Keywords: Prealbumin -retinol-binding protein -thyroid hormones - specificity of binding - heterogeneity.
Department/Centre: Division of Biological Sciences > Biochemistry
Date Deposited: 06 Oct 2010 09:39
Last Modified: 01 Mar 2019 05:26
URI: http://eprints.iisc.ac.in/id/eprint/32996

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