Cation Translocating Effects of Alamethicin and its Synthetic Fragments in Lipid Membranes: Influence of peptide chain length and charge

Nagaraj, R and Mathew, MK and Balaram, P (1980) Cation Translocating Effects of Alamethicin and its Synthetic Fragments in Lipid Membranes: Influence of peptide chain length and charge. In: FEBS Letters, 121 (2). pp. 365-368.

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Abstract

Alamethicin, a 20 residue polypeptide ionophore forms transmembrane channels and has been shown to induce excitability phenomena in artificial lipid membranes [1]. The discovery of a number of related polypeptides, containing \alpha-aminoisobutyric acid (Aib) [2], has stimulated considerable interest in the conformational analysis of Aib peptides, with a view towards establishing the structural requirements for formation of membrane channels [3-5].

Item Type:	Journal Article
Publication:	FEBS Letters
Publisher:	Elsevier
Additional Information:	Copyright for this article belongs to Elsevier Science Ltd.
Department/Centre:	Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited:	04 Apr 2005
Last Modified:	19 Sep 2010 04:18
URI:	http://eprints.iisc.ac.in/id/eprint/3030

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