Experimental investigation of perturbation Monte-Carlo based derivative estimation for imaging low-scattering tissue

Yalavarthy, Phaneendra K and Karlekar, Kirtish and Patel, HS and Vasu, RM and Pramanik, Manojit and Mathias, PC and Jain, B and Gupta, PK (2005) Experimental investigation of perturbation Monte-Carlo based derivative estimation for imaging low-scattering tissue. In: Optics Express, 13 (3). pp. 985-997.

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Abstract

Experimental results for imaging the low-scattering tissue phantoms based on the derivative estimation through perturbation Monte- Carlo (pMC) method are presented. It is proven that pMC-based methods give superior reconstructions compared to diffusion-based reconstruction methods. An easy way to estimate the Jacobian using analytical expression obtained from perturbation Monte-Carlo method is employed. Simulation studies on the same objects, considered in the experiment, are performed and corresponding results are found to be in reasonable agreement with the experimental studies. It is shown that inter-parameter cross talk in diffusion based methods lead to false results for the low-scattering tissue, where as the pMC-based method gives accurate results.

Item Type:	Journal Article
Publication:	Optics Express
Publisher:	Optical Society of America (OSA)
Additional Information:	Copyright for this article belongs to Optical Society of America (OSA).
Keywords:	Optical diagnostics for medicine;Inverse problems;Light propagation in tissues;Medical optics and biotechnology
Department/Centre:	Division of Physical & Mathematical Sciences > Instrumentation Appiled Physics Division of Chemical Sciences > Sophisticated Instruments Facility (Continued as NMR Research Centre)
Date Deposited:	25 Aug 2008
Last Modified:	19 Sep 2010 04:18
URI:	http://eprints.iisc.ac.in/id/eprint/2770

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