Observation of a power-law memory kernel for fluctuations within a single protein molecule

Min, Wei and Binny, Guobin Luo and Cherayil, Binny J and Kou, SC and Xie, X Sunney (2005) Observation of a power-law memory kernel for fluctuations within a single protein molecule. In: Physical Review Letters, 94 (19).

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Abstract

The fluctuation of the distance between a fluorescein-tyrosine pair within a single protein complex was directly monitored in real time by photoinduced electron transfer and found to be a stationary, time-reversible, and non-Markovian Gaussian process. Within the generalized Langevin equation formalism, we experimentally determine the memory kernel K(t), which is proportional to the autocorrelation function of the random fluctuating force. K(t) is a power-law decay, t(-0.51 +/- 0.07) in a broad range of time scales (10(-3)-10 s). Such a long-time memory effect could have implications for protein functions.

Item Type:	Journal Article
Publication:	Physical Review Letters
Publisher:	The American Physical Society
Additional Information:	Copyright of this article belongs to The American Physical Society.
Department/Centre:	Division of Chemical Sciences > Inorganic & Physical Chemistry
Date Deposited:	04 Jun 2010 10:01
Last Modified:	19 Sep 2010 06:01
URI:	http://eprints.iisc.ac.in/id/eprint/27564

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