Electronic Control of Facial Selection in Additions to Sterically Unbiased Ketones and Olefins

Mehta, Goverdhan and Chandrasekhar, Jayaraman (1999) Electronic Control of Facial Selection in Additions to Sterically Unbiased Ketones and Olefins. In: Chemical Reviews, 99 (5). pp. 1437-1467.

PDF cr980369v.pdf - Published Version Restricted to Registered users only Download (665kB) | Request a copy

Abstract

By definition, the two faces of a pi bond are equivalent.1 However, they are rendered nonequivalent in most molecules because of the absence of a plane of symmetry encompassing the double bond and the adjacent substituents. As a result, additions to trigonal centers from the two faces need not be equally facile. Exploiting this stereodifferentiation in a controlled manner represents one of the core problems in organic synthesis. Evidently, the factors which determine such diastereoselection need to be delineated in as much detail as possible.

Item Type:	Journal Article
Publication:	Chemical Reviews
Publisher:	American Chemical Society
Additional Information:	Copyright of this article belongs to American Chemical Society.
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	03 Jun 2009 05:09
Last Modified:	19 Sep 2010 05:27
URI:	http://eprints.iisc.ac.in/id/eprint/19227

Actions (login required)

View Item