Kasturi, TR and Jois, HRY (1990) Synthesis of 7-alkyl-4-cyano-3-methoxy-1-methyl-5,6-dihydroisoquinoline. In: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 29 (7). pp. 615-619.
Full text not available from this repository. (Request a copy)Abstract
Knoevenagel condensation of 2-acylcyclohexanones with cyanoacetamide followed by silver salt methylation gives 5,6,7,8-tetrahydroisoquinolines I (R = H, Me, Me3C). Chromic acid oxidn. of I leads to tetralones, which were reduced with borohydride and the alcs. dehydrated by p-toluenesulfonic acid to give the corresponding 5,6-dihydroisoquinolines II (same R).
| Item Type: | Journal Article |
|---|---|
| Publication: | Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry |
| Publisher: | National Institute of Science Communication and Information Resources |
| Additional Information: | The copyright belongs to National Institute of Science Communication and Information Resources |
| Department/Centre: | Division of Chemical Sciences > Organic Chemistry |
| Date Deposited: | 11 Feb 2008 |
| Last Modified: | 27 Aug 2008 13:07 |
| URI: | http://eprints.iisc.ac.in/id/eprint/12698 |
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