Facile Synthesis, Aggregation Behavior, and Cholesterol Solubilization Ability of Avicholic Acid

Mukhopadhyay, Samrat and Maitra, Uday (2004) Facile Synthesis, Aggregation Behavior, and Cholesterol Solubilization Ability of Avicholic Acid. In: Organic Letters, 6 (1). pp. 31-34.

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Abstract

Avicholic acid, a major constituent of the bile of several avian species, was synthesized in eight steps from readily available chenodeoxycholic acid in 9% overall yield using Breslow’s remote functionalization strategy in a key step. Micelle formation and equilibrium cholesterol solubilization properties were studied for avicholate in aqueous solution.

Item Type:	Journal Article
Publication:	Organic Letters
Publisher:	American Chemical Society
Additional Information:	The copyright of this article belongs to American Chemical Society.
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	02 Jun 2006
Last Modified:	19 Sep 2010 04:28
URI:	http://eprints.iisc.ac.in/id/eprint/7405

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