Synthetic Approaches to Halogen Bonded Ternary Cocrystals

Jain, H and Sutradhar, D and Roy, S and Desiraju, GR (2021) Synthetic Approaches to Halogen Bonded Ternary Cocrystals. In: Angewandte Chemie - International Edition, 60 (23). pp. 12841-12846.

	PDF anie202103516-sup-0001-misc_information.pdf - Published Supplemental Material Restricted to Registered users only Download (1MB) | Request a copy
	PDF ang_che_int_edi_60-23_12841-12846_2021.pdf - Published Version Restricted to Registered users only Download (1MB) | Request a copy

Abstract

Higher cocrystal synthesis depends acutely on a knowledge of supramolecular synthons. We report three synthetic approaches towards ternary halogen bonded cocrystals that illustrate specificity and generality. Electrophilicity/nucleophilicity differences are needed among alternative sites of halogen bond formation. The two halogen bonds Aâ� â� â� B and Bâ� â� â� C in a halogen bonded ternary cocrystal ABC need to be of different strength. Interaction mimicry of hydrogen bonds by halogen bonds is a viable approach towards ternaries as illustrated with the pyrene structure. Finally, the crystal engineer should well be able to anticipate halogen bonds that are stronger than hydrogen bonds. © 2021 Wiley-VCH GmbH

Item Type:	Journal Article
Publication:	Angewandte Chemie - International Edition
Publisher:	John Wiley and Sons Inc
Additional Information:	The copyright for this article belongs to John Wiley and Sons Inc
Keywords:	Chemical engineering; Chemical reactions; Chemistry, Co-crystals; Electrophilicity; Halogen bonds; Supramolecular synthons; Synthetic approach; Ternary cocrystals, Hydrogen bonds
Department/Centre:	Division of Chemical Sciences > Solid State & Structural Chemistry Unit
Date Deposited:	27 Jul 2021 10:45
Last Modified:	27 Jul 2021 10:45
URI:	http://eprints.iisc.ac.in/id/eprint/68960

Actions (login required)

View Item