A Miniature Wireless Silicon-on-Insulator Image Sensor for Brain Fluorescence Imaging

Zhang, J and Khalifa, A and Spetalnick, S and Alemohammad, M and Rattray, J and Thakur, CS and Eisape, A and Etienne-Cummings, R (2020) A Miniature Wireless Silicon-on-Insulator Image Sensor for Brain Fluorescence Imaging. In: 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society, EMBC, 20-24 July 2020, Montreal; Canada, pp. 3403-3406.

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Abstract

Optical recording of genetically encoded calcium indicator (GECI) allows neuroscientists to study the activity of genetically labeled neuron populations, but our current tools lack the resolution, stability and are often too invasive. Here we present the design concepts, prototypes, and preliminary measurement results of a super-miniaturized wireless image sensor built using a 32nm Silicon-on-Insulator process. SOI process is optimal for wireless applications, and we can further thin the substrate to reduce overall device thickness to ~25μm and operate the pixels using back-side illumination. The proposed device is 300μm � 300μm. Our prototype is built on a 3 � 3mm die. © 2020 IEEE.

Item Type:	Conference Paper
Publication:	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Publisher:	Institute of Electrical and Electronics Engineers Inc.
Additional Information:	The copyright of this article belongs to Institute of Electrical and Electronics Engineers Inc.
Keywords:	Fluorescence imaging; Image sensors; Silicon on insulator technology, Calcium indicator; Design concept; Neuron population; Silicon-on-insulator process; Wireless application, Image processing
Department/Centre:	Division of Electrical Sciences > Electronic Systems Engineering (Formerly Centre for Electronic Design & Technology)
Date Deposited:	29 Sep 2020 08:55
Last Modified:	29 Sep 2020 08:55
URI:	http://eprints.iisc.ac.in/id/eprint/66689

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