ePrints@IIScePrints@IISc Home | About | Browse | Latest Additions | Advanced Search | Contact | Help

Coupling Electrochemical Adsorption and Long-range Electron Transfer: Label-free DNA Mismatch Detection with Ultramicroelectrode (UME)

Basu, Nivedita and Ho, Thu Huong and Guillon, Francois-Xavier and Zhang, Yuanyuan and Bigey, Pascal and Navakanta, Bhat and Bedioui, Fethi and Lazerges, Mathieu (2019) Coupling Electrochemical Adsorption and Long-range Electron Transfer: Label-free DNA Mismatch Detection with Ultramicroelectrode (UME). In: ELECTROANALYSIS .

[img] PDF
ele_ana_2019.pdf - Published Version
Restricted to Registered users only

Download (1MB) | Request a copy
[img]
Preview
PDF
elan201900357-sup-0001-misc_information.pdf - Published Supplemental Material

Download (584kB) | Preview
Official URL: https://dx.doi.org/10.1002/elan.201900357

Abstract

A new electrochemical hybridization transduction pathway, obtained by coupling electrochemical adsorption and long-range electron transfer through double-stranded DNA, was investigated using ultramicroelectrode (UME). The results show that long-range electron transfer does not occurs exclusively throws well-packed and organized self-assembled DNA monolayers. This approach is used to investigate long-range electron transfer properties of both single- and double- stranded short synthetic DNA and DNA plasmids. Single mismatch electrochemical detection protocol of non-labelled short synthetic DNA, without heating or probe labelling, in a 10 minutes protocol, was in fine performed.

Item Type: Journal Article
Additional Information: copyright for this article belongs to WILEY-V C H VERLAG GMBH
Department/Centre: Division of Electrical Sciences > Electrical Communication Engineering
Division of Interdisciplinary Research > Centre for Nano Science and Engineering
Depositing User: Id for Latest eprints
Date Deposited: 05 Aug 2019 08:58
Last Modified: 05 Aug 2019 08:58
URI: http://eprints.iisc.ac.in/id/eprint/63371

Actions (login required)

View Item View Item