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Visible-Light-Mediated Direct Decarboxylative Acylation of Electron-Deficient Heteroarenes Using alpha-Ketoacids

Manna, Sabyasachi and Prabhu, Kandikere Ramaiah (2019) Visible-Light-Mediated Direct Decarboxylative Acylation of Electron-Deficient Heteroarenes Using alpha-Ketoacids. In: JOURNAL OF ORGANIC CHEMISTRY, 84 (9). pp. 5067-5077.

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Official URL: https://doi.org/10.1021/acs.joc.9b00004

Abstract

Acylation of electron-deficient heteroaromatic compounds has been developed using visible light. alpha-Ketoacids have been used as an efficient source of acyl radicals under photoredox conditions. The in situ generated acyl radicals from alpha-ketoacids have been coupled to a wide variety of electron-deficient heteroaromatic compounds in a Minisci type reaction. This method would be attractive to access biologically attractive molecules.

Item Type: Journal Article
Additional Information: copyright for this article belongs to JOURNAL OF ORGANIC CHEMISTRY
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Depositing User: Id for Latest eprints
Date Deposited: 24 Jun 2019 18:08
Last Modified: 24 Jun 2019 18:08
URI: http://eprints.iisc.ac.in/id/eprint/63067

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