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FPGA-Based Lock-In Amplifier for Measuring the Electrical Properties of Individual Cells

Divakar, Dipin and Mahesh, Karthik and Varma, Manoj M and Sen, Prosenjit (2018) FPGA-Based Lock-In Amplifier for Measuring the Electrical Properties of Individual Cells. In: Proceedings of the 13th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, 22-26 April, 2018, Singapore, pp. 413-416.

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Official URL: https://dx.doi.org/10.1109/NEMS.2018.8556987

Abstract

We report the design and validation of a low-cost and portable FPGA-based lock-in amplifier (LIA) for measuring the dielectric properties of cells through electrical impedance spectroscopy (EIS). The proposed design uses the phase sensitive measurement principle which detects the signal at a particular reference frequency and rejects the rest. By closely integrating the LIA with a custom-built instrumentation amplifier and a microfluidic device, we demonstrate the excellent ability of the system to suppress noise and detect impedance changes due to flowing red blood cells (RBCs).

Item Type: Conference Proceedings
Additional Information: 13th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems (IEEE-NEMS), Singapore, SINGAPORE, APR 22-26, 2018
Department/Centre: Division of Interdisciplinary Research > Centre for Nano Science and Engineering
Depositing User: R.S. Ranganayaki
Date Deposited: 05 Jul 2019 06:21
Last Modified: 05 Jul 2019 06:21
URI: http://eprints.iisc.ac.in/id/eprint/62819

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